Name: | Apoptotic Protease-Activating Factor 1 |
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Description: | A CARD signaling adaptor protein that plays a role in the mitochondria-stimulated apoptosis (APOPTOSIS, INTRINSIC PATHWAY). It binds to CYTOCHROME C in the CYTOSOL to form an APOPTOSOMAL PROTEIN COMPLEX and activates INITIATOR CASPASES such as CASPASE 9. |
Synonyms: |
Protease-Activating Factor, Apaf-1; Apaf 1 Protease Activating Factor; Apaf-1 Protease-Activating Factor; Apoptotic Protease Activating Factor 1
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