QuickView for APIP;jsessionid=A13734933D0B92C4FE7E591F1893FF6D (gene)
- Gene Symbol:
- APIP
Homo sapiens - Full name:
- APAF1 interacting protein
- Synonyms:
- APIP2, CGI-29, CGI29, MMRP19, hAPIP, methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase, probable methylthioribulose-1-phosphate dehydratase
- Genomic Location:
- Chr 11: 34860421-34894484
- Description:
-
APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury (Cho et al., 2004 [PubMed 15262985]).
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Gallus gallus , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
11p13
GO Molecular Function
cation binding | hydro-lyase activity | lyase activity | methylthioribulose 1-phosphate dehydratase activity | catalytic activity | identical protein binding | ion binding | protein binding | zinc ion binding | transition metal ion binding | metal ion binding
GO Biological Process
regulation of ERK1 and ERK2 cascade | protein homooligomerization | sulfur compound metabolic process | regulation of programmed cell death | negative regulation of cellular process | cellular process | negative regulation of apoptotic process | sulfur amino acid biosynthetic process | L-methionine salvage | cellular amino acid metabolic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | cellular component organization | cellular amino acid biosynthetic process | programmed cell death | cellular component assembly | cellular biosynthetic process | apoptotic process | sulfur amino acid metabolic process | nitrogen compound metabolic process | regulation of signal transduction | regulation of MAPK cascade | protein complex oligomerization | regulation of phosphorylation | regulation of nitrogen compound metabolic process | small molecule metabolic process | methionine metabolic process | protein homotetramerization | biosynthetic process | regulation of cellular protein metabolic process | protein tetramerization | regulation of cellular metabolic process | regulation of protein metabolic process | regulation of protein phosphorylation | drug metabolic process | carboxylic acid metabolic process | protein-containing complex assembly | regulation of intracellular signal transduction | methionine biosynthetic process | metabolic process | negative regulation of programmed cell death | organic substance metabolic process | cell death | regulation of phosphate metabolic process | L-methionine salvage from methylthioadenosine | regulation of cell communication | organic acid metabolic process | cellular metabolic process | regulation of cell death | negative regulation of cell death | pyroptosis | regulation of signaling | regulation of phosphorus metabolic process
