QuickView for AQP7;jsessionid=BE0D63F12B7593106BAA6E012C1D62C1 (gene)

Gene Symbol:

AQP7 Homo sapiens

Full name:

aquaporin 7

Synonyms:

AQP7L, AQPap, GLYCQTL, aquaporin-7, aquaglyceroporin-7, aquaporin adipose

Genomic Location:

Chr 9: 33374948-33392517

Description:

This gene encodes a member of the aquaporin family of water-selective membrane channels. The encoded protein localizes to the plasma membrane and allows movement of water, glycerol and urea across cell membranes. This gene is highly expressed in the adipose tissue where the encoded protein facilitates efflux of glycerol. In the proximal straight tu...

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This gene encodes a member of the aquaporin family of water-selective membrane channels. The encoded protein localizes to the plasma membrane and allows movement of water, glycerol and urea across cell membranes. This gene is highly expressed in the adipose tissue where the encoded protein facilitates efflux of glycerol. In the proximal straight tubules of kidney, the encoded protein is localized to the apical membrane and prevents excretion of glycerol into urine. The encoded protein is present in spermatids, as well as in the testicular and epididymal spermatozoa suggesting an important role in late spermatogenesis. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. This gene is located adjacent to a related aquaporin gene on chromosome 9. Multiple pseudogenes of this gene have been identified.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

YTATTTTNR_MEF2_02 ,  YGACNNYACAR_UNKNOWN ,  ARP1_01 ,  TGACCTY_ERR1_Q2 ,  ATF1_Q6 ,  PPAR_DR1_Q2

Cytogenetic Map:

9p13.3

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