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QuickView for ARHI (gene)


Gene Symbol:
DIRAS3 Homo sapiens Homo sapiens
Full name:
DIRAS family GTPase 3
Synonyms:
ARHI, NOEY2, GTP-binding protein Di-Ras3, DIRAS family, GTP-binding RAS-like 3, distinct subgroup of the Ras family member 3, ras homolog gene family, member I, rho-related GTP-binding protein RhoI
Genomic Location:
Chr 1: 68284233-68289048
Description:
This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer ce...
Orthologs:
Macaca mulatta Pan troglodytes Bos taurus
External Links:
Entrez Gene
Cytogenetic Map:
chr 1
1p31.3


Transcripts Names
NM_004675
Protein Names
B3KMP3
O95661



GO Molecular Function

guanyl ribonucleotide binding | ribonucleoside binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | pyrophosphatase activity | catalytic activity | anion binding | nucleoside-triphosphatase activity | purine nucleotide binding | ion binding | organic cyclic compound binding | GTPase activity | purine nucleoside binding | purine ribonucleoside triphosphate binding | protein binding | GTP binding | hydrolase activity, acting on acid anhydrides | nucleoside binding | purine ribonucleotide binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | guanyl nucleotide binding | small molecule binding

GO Biological Process

intracellular signal transduction | cellular process | regulation of gene expression, epigenetic | regulation of cell cycle | regulation of cellular process | regulation of metabolic process | small GTPase mediated signal transduction | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | genetic imprinting | cellular nitrogen compound metabolic process | regulation of cyclin-dependent protein serine/threonine kinase activity | nitrogen compound metabolic process | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of gene expression | regulation of nitrogen compound metabolic process | regulation of cellular protein metabolic process | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | regulation of protein phosphorylation | regulation of gene expression by genetic imprinting | regulation of kinase activity | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | regulation of phosphate metabolic process | signaling | heterocycle metabolic process | cellular metabolic process | signal transduction | regulation of phosphorus metabolic process

GO Cellular Component

cell | plasma membrane | cell periphery | intracellular | membrane