QuickView for ASIC2 (gene)

Gene Symbol:

ASIC2 Homo sapiens

Full name:

acid sensing ion channel subunit 2

Synonyms:

ACCN, ACCN1, ASIC2a, BNC1, BNaC1, MDEG, hBNaC1, acid-sensing ion channel 2, acid sensing (proton gated) ion channel 2, amiloride-sensitive cation channel 1, neuronal, brain sodium channel 1, mammalian degenerin homolog, neuronal amiloride-sensitive cation channel 1

Genomic Location:

Chr 17: 28364218-29507938

Description:

This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded ...

View Full Description

This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Danio rerio ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  IRF1_01 ,  RTAAACA_FREAC2_01 ,  CACTGCC_MIR34A_MIR34C_MIR449 ,  FREAC7_01 ,  HFH3_01 ,  GATA3_01 ,  FOXO4_01 ,  GCANCTGNY_MYOD_Q6 ,  GGGACCA_MIR133A_MIR133B ,  CIZ_01 ,  WGTTNNNNNAAA_UNKNOWN ,  STAT6_01 ,  AMEF2_Q6 ,  GATAAGR_GATA_C ,  MYB_Q5_01 ,  OCT1_Q5_01 ,  TTAYRTAA_E4BP4_01 ,  TATAAA_TATA_01 ,  EVI1_03 ,  STAT3_02 ,  SREBP1_01 ,  TITF1_Q3 ,  YYCATTCAWW_UNKNOWN ,  RP58_01 ,  NFY_Q6_01 ,  LFA1_Q6 ,  P53_02 ,  CAGGTG_E12_Q6 ,  E47_02 ,  EVI1_02 ,  AP2_Q6_01 ,  EVI1_05 ,  YGCANTGCR_UNKNOWN ,  STAT5A_03 ,  LMO2COM_02 ,  AHR_Q5 ,  EVI1_06 ,  AP2_Q3 ,  HFH4_01 ,  HFH8_01 ,  RNGTGGGC_UNKNOWN ,  FREAC2_01 ,  TTGTTT_FOXO4_01 ,  CART1_01 ,  PIT1_Q6 ,  RTTTNNNYTGGM_UNKNOWN ,  TEF_Q6 ,  PAX_Q6 ,  GTGGGTGK_UNKNOWN ,  CAGCTG_AP4_Q5 ,  LXR_Q3 ,  MMEF2_Q6 ,  BRN2_01 ,  PAX4_03 ,  PAX2_02 ,  CTGRYYYNATT_UNKNOWN ,  RACTNNRTTTNC_UNKNOWN ,  GGGTGGRR_PAX4_03 ,  MYB_Q3 ,  MEF2_Q6_01

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-133 ,  Predicted Gene Targets for miR-143 ,  Predicted Gene Targets for miR-34

Cytogenetic Map:

17q11.2-q12

search → result