QuickView for AT1R (gene)

Gene Symbol:

AGTR1 Homo sapiens

Full name:

angiotensin II receptor type 1

Synonyms:

AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, HAT1R, type-1 angiotensin II receptor, type-1B angiotensin II receptor

Genomic Location:

Chr 3: 149898348-149943480

Description:

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiot...

View Full Description

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TATAAA_TATA_01 ,  TGACAGNY_MEIS1_01 ,  TGACATY_UNKNOWN

miRNA binding sites
(Source: miRecords):

hsa-miR-155 Targeted Genes

Cytogenetic Map:

3q24

search → result