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QuickView for AT2R (gene)


Gene Symbol:
Agtr2 Rattus norvegicus Rattus norvegicus
Full name:
angiotensin II receptor, type 2
Synonyms:
AT2-R, AT2R, AT<sub>2</sub>R, type-2 angiotensin II receptor, AT2, angiotensin II type 2 receptor, angiotensin receptor 2
Genomic Location:
Chr Un: 50646357-50650523
Description:
receptor for angiotensin II; vasodilator that regulates many actions in vascular smooth muscle cells and during development
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Canis lupus familiaris Bos taurus Gallus gallus Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_012494
XM_006257432
Protein Names
P35351
B1WBL8



GO Molecular Function

peptide binding | peptide hormone binding | transmembrane signaling receptor activity | angiotensin type II receptor activity | G-protein coupled receptor activity | amide binding | signaling receptor activity | hormone binding | protein binding | transcription factor binding | angiotensin receptor activity | peptide receptor activity | G-protein coupled peptide receptor activity | G-protein alpha-subunit binding

GO Biological Process

brain development | regulation of neurotrophin TRK receptor signaling pathway | regulation of blood vessel diameter | positive regulation of macromolecule biosynthetic process | regulation of dephosphorylation | regulation of intracellular protein transport | regulation of systemic arterial blood pressure by hormone | regulation of cellular localization | muscle tissue development | intracellular signal transduction | positive regulation of apoptotic process | regulation of localization | catechol-containing compound metabolic process | lipid transport | regulation of programmed cell death | hormone secretion | establishment of localization | response to hormone | positive regulation of phosphoprotein phosphatase activity | negative regulation of neuron death | cell growth involved in cardiac muscle cell development | negative regulation of cellular process | positive regulation of developmental process | regulation of phosphatase activity | response to dexamethasone | regulation of protein import | cell differentiation | angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure | striated muscle cell development | defense response | nervous system development | response to drug | organ growth | cellular chemical homeostasis | neurogenesis | positive regulation of phosphate metabolic process | regulation of renal sodium excretion | generation of neurons | positive regulation of protein secretion | negative regulation of heart rate | cardiac cell development | regulation of lipid transport | phenol-containing compound metabolic process | regulation of neuron death | positive regulation of dephosphorylation | positive regulation of cellular biosynthetic process | cellular process | secretion | positive regulation of glomerulus development | regulation of catecholamine secretion | localization | cellular homeostasis | exploration behavior | negative regulation of signaling | developmental growth | cellular sodium ion homeostasis | positive regulation of nitric-oxide synthase activity | aldosterone secretion | macromolecule localization | negative regulation of apoptotic process | negative regulation of secretion | positive regulation of oxidoreductase activity | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | response to peptide hormone | tissue development | muscle structure development | muscle cell differentiation | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | neurological system process involved in regulation of systemic arterial blood pressure | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | positive regulation of renal sodium excretion | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | regulation of systemic arterial blood pressure mediated by a chemical signal | urogenital system development | angiotensin type II receptor activity | head development | G-protein coupled receptor activity | regulation of peptide secretion | response to stimulus | muscle cell development | regulation of cellular protein localization | metencephalon development | regulation of excretion | positive regulation of protein metabolic process | regulation of blood vessel size | regulation of norepinephrine secretion | cellular response to xenobiotic stimulus | response to stress | renin-angiotensin regulation of aldosterone production | regulation of cell proliferation | regulation of blood circulation | response to peptide | cardiac muscle tissue development | positive regulation of phosphatase activity | physiological cardiac muscle hypertrophy | regulation of heart rate | secretion by cell | organic hydroxy compound transport | positive regulation of cytokine secretion | negative regulation of transport | catecholamine biosynthetic process | cellular response to organic cyclic compound | metanephros morphogenesis | regulation of protein transport | blood circulation | G-protein coupled receptor signaling pathway | positive regulation of RNA biosynthetic process | regulation of peptide transport | cellular biosynthetic process | kidney development | heart growth | regulation of morphogenesis of a branching structure | cell-cell signaling | dopamine metabolic process | positive regulation of protein dephosphorylation | regulation of metanephros size | regulation of intracellular transport | metal ion homeostasis | negative regulation of blood pressure | regulation of nucleic acid-templated transcription | positive regulation of peptide secretion | positive regulation of monooxygenase activity | organic hydroxy compound metabolic process | response to nitrogen compound | negative regulation of neuron apoptotic process | cellular response to hormone stimulus | system development | sodium ion homeostasis | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of secretion by cell | multicellular organism development | cellular response to peptide hormone stimulus | regulation of catalytic activity | cerebellum development | kidney morphogenesis | regulation of hormone levels | regulation of hormone secretion | regulation of nitric-oxide synthase activity | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | positive regulation of secretion | organic substance transport | response to ketone | response to lipid | nervous system process | cellular response to peptide | regulation of blood pressure | regulation of systemic arterial blood pressure by renin-angiotensin | regulation of systemic arterial blood pressure | positive regulation of cellular metabolic process | cellular ion homeostasis | animal organ morphogenesis | regulation of protein localization to nucleus | regulation of nitrogen compound metabolic process | negative regulation of cellular response to growth factor stimulus | cardiocyte differentiation | response to corticosteroid | dopamine biosynthetic process | negative regulation of norepinephrine secretion | positive regulation of hydrolase activity | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger | cardiac muscle hypertrophy | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | cardiac muscle cell development | cellular response to glucocorticoid stimulus | hindbrain development | regulation of blood volume by renin-angiotensin | negative regulation of ion transport | regulation of apoptotic signaling pathway | response to xenobiotic stimulus | regulation of heart contraction | cation homeostasis | cellular response to corticosteroid stimulus | cellular response to angiotensin | cellular response to drug | angiotensin-activated signaling pathway | striated muscle tissue development | cellular cation homeostasis | endocrine process | positive regulation of extrinsic apoptotic signaling pathway | cell communication | regulation of cellular metabolic process | regulation of neuron apoptotic process | metanephros development | inflammatory response | regulation of endocrine process | regulation of protein metabolic process | positive regulation of signal transduction | heart development | homeostatic process | positive regulation of cell proliferation | positive regulation of establishment of protein localization | regulation of RNA metabolic process | renal system development | regulation of tube size | positive regulation of transport | striated muscle cell differentiation | regulation of cellular response to growth factor stimulus | negative regulation of catecholamine secretion | cardiac muscle tissue growth | drug metabolic process | positive regulation of molecular function | regulation of nucleocytoplasmic transport | regulation of cytokine secretion | response to angiotensin | neuron differentiation | negative regulation of lipid transport | regulation of fibroblast proliferation | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | regulation of protein import into nucleus | regulation of protein dephosphorylation | catecholamine metabolic process | response to antineoplastic agent | regulation of animal organ morphogenesis | positive regulation of metanephric glomerulus development | anatomical structure development | cell surface receptor signaling pathway | vasodilation | metabolic process | lipid localization | negative regulation of fatty acid transport | positive regulation of branching involved in ureteric bud morphogenesis | regulation of RNA biosynthetic process | negative regulation of programmed cell death | regulation of tube diameter | cerebellar cortex development | negative regulation of heart contraction | chemical homeostasis | brain renin-angiotensin system | regulation of secretion | behavior | positive regulation of cell death | hormone transport | organic substance metabolic process | animal organ development | regulation of protein secretion | positive regulation of programmed cell death | regulation of kidney size | ion homeostasis | negative regulation of neurotrophin TRK receptor signaling pathway | regulation of phosphate metabolic process | angiotensin receptor activity | cellular response to steroid hormone stimulus | renal system process | regulation of systemic arterial blood pressure by circulatory renin-angiotensin | negative regulation of icosanoid secretion | positive regulation of cytokine production | cellular response to dexamethasone stimulus | positive regulation of protein transport | cardiac muscle cell differentiation | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | negative regulation of signal transduction | signaling | G-protein coupled peptide receptor activity | regulation of transcription, DNA-templated | regulation of oxidoreductase activity | response to organic cyclic compound | cellular monovalent inorganic cation homeostasis | negative regulation of systemic arterial blood pressure | cell development | negative regulation of fibroblast proliferation | regulation of cytokine production | anatomical structure morphogenesis | regulation of developmental process | regulation of ion transport | regulation of phosphoprotein phosphatase activity | renal system process involved in regulation of systemic arterial blood pressure | developmental process | regulation of transport | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | developmental cell growth | regulation of fatty acid transport | positive regulation of kidney development | positive regulation of nucleic acid-templated transcription | signal release | response to organonitrogen compound | cellular metal ion homeostasis | regulation of anion transport | regulation of branching involved in ureteric bud morphogenesis | central nervous system development | positive regulation of metabolic process | cellular metabolic process | cellular response to organic substance | regulation of protein localization | regulation of cell death | response to steroid hormone | regulation of blood vessel diameter by renin-angiotensin | negative regulation of cell death | positive regulation of blood vessel diameter | circulatory system development | muscle hypertrophy | positive regulation of apoptotic signaling pathway | muscle system process | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | response to glucocorticoid | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | cytoplasm | plasma membrane | perinuclear region of cytoplasm | cell periphery | intracellular | membrane