QuickView for ATG12 (gene)

Gene Symbol:

ATG12 Homo sapiens

Full name:

autophagy related 12

Synonyms:

APG12, APG12L, FBR93, HAPG12, ubiquitin-like protein ATG12, APG12 autophagy 12-like, ATG12 autophagy related 12 homolog, Apg12 (autophagy, yeast) homolog

Genomic Location:

Chr 5: 115193714-115205398

Description:

Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).

Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Danio rerio ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TAL1ALPHAE47_01 ,  MZF1_01 ,  NGFIC_01 ,  MEIS1BHOXA9_01 ,  GGGAGGRR_MAZ_Q6 ,  RREB1_01 ,  EGR_Q6 ,  NF1_Q6 ,  GGGCGGR_SP1_Q6 ,  YKACATTT_UNKNOWN ,  AHR_Q5 ,  GATA1_02 ,  RNGTGGGC_UNKNOWN ,  YGCGYRCGC_UNKNOWN ,  TGACAGNY_MEIS1_01 ,  EGR1_01 ,  PAX4_03 ,  TGACATY_UNKNOWN ,  GGGTGGRR_PAX4_03

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Cytogenetic Map:

5q22.3

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