QuickView for ATP2C1 (gene)

Gene Symbol:

ATP2C1 Homo sapiens

Full name:

ATPase secretory pathway Ca2+ transporting 1

Synonyms:

ATP2C1A, BCPM, HHD, PMR1, SPCA1, hSPCA1, calcium-transporting ATPase type 2C member 1, ATP-dependent Ca(2+) pump PMR1, ATPase 2C1, ATPase, Ca(2+)-sequestering, ATPase, Ca++ transporting, type 2C, member 1, HUSSY-28, secretory pathway Ca2+/Mn2+ ATPase 1

Genomic Location:

Chr 3: 132096124-132218246

Description:

The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms...

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The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  TTTGCAC_MIR19A_MIR19B ,  GATA3_01 ,  YTATTTTNR_MEF2_02 ,  TTCNRGNNNNTTC_HSF_Q6 ,  LYF1_01 ,  ARP1_01 ,  WGTTNNNNNAAA_UNKNOWN ,  IRF1_Q6 ,  RGAANNTTC_HSF1_01 ,  DBP_Q6 ,  TGCAAAC_MIR452 ,  GGGYGTGNY_UNKNOWN ,  TTCYRGAA_UNKNOWN ,  ATGTTAA_MIR302C ,  MGGAAGTG_GABP_B ,  HSF_Q6 ,  TGTTTGY_HNF3_Q6 ,  SCGGAAGY_ELK1_02 ,  ZIC2_01 ,  CTGCAGY_UNKNOWN ,  PAX_Q6 ,  TGCACTT_MIR519C_MIR519B_MIR519A ,  TGACAGNY_MEIS1_01 ,  CTTTGT_LEF1_Q2 ,  RCGCANGCGY_NRF1_Q6 ,  CTAGGAA_MIR384 ,  GTTAAAG_MIR302B

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-153 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-26 ,  Predicted Gene Targets for miR-448 ,  Predicted Gene Targets for miR-93 ,  Predicted Gene Targets for miR-384 ,  Predicted Gene Targets for miR-452

Cytogenetic Map:

3q22.1

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