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QuickView for ATP8B3;jsessionid=EEB3ED6114D8135F10FC34B3C4D400D2 (gene)


Gene Symbol:
ATP8B3 Homo sapiens Homo sapiens
Full name:
ATPase phospholipid transporting 8B3
Synonyms:
ATPIK, phospholipid-transporting ATPase IK, ATPase, aminophospholipid transporter, class I, type 8B, member 3, ATPase, class I, type 8B, member 3, aminophospholipid translocase ATP8B3, potential phospholipid-transporting ATPase IK, probable phospholipid-transporting ATPase IK
Genomic Location:
Chr 19: 1733074-1763270
Description:
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to the other. This gene encodes member 3 of phospholipid-transporting ATPas...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Danio rerio Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 19
19p13.3





GO Molecular Function

cation binding | magnesium ion binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | phospholipid transporter activity | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | purine nucleotide binding | transporter activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | metal ion binding | lipid transporter activity | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding | phospholipid-translocating ATPase activity

GO Biological Process

lipid transport | establishment of localization | membrane organization | cellular process | localization | anion transport | macromolecule localization | endomembrane system organization | regulation of membrane lipid distribution | cell recognition | cellular component organization | sperm-egg recognition | reproduction | reproductive process | phospholipid transporter activity | binding of sperm to zona pellucida | organic substance transport | cell-cell recognition | fertilization | organic anion transport | single fertilization | phospholipid transport | Golgi organization | lipid localization | organelle organization | phospholipid translocation | lipid transporter activity | ion transport | sexual reproduction | phospholipid-translocating ATPase activity

GO Cellular Component

secretory granule | integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | acrosomal vesicle | intracellular organelle | endoplasmic reticulum | secretory granule membrane | Golgi apparatus | nuclear outer membrane-endoplasmic reticulum membrane network | secretory vesicle | endomembrane system | endoplasmic reticulum membrane | plasma membrane | vesicle | acrosomal membrane | membrane-bounded organelle | organelle | vesicle membrane | cell periphery | intracellular vesicle | intracellular | membrane | cytoplasmic vesicle membrane