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QuickView for Actg1 (gene)


Gene Symbol:
ACTG1 Homo sapiens Homo sapiens
Full name:
actin gamma 1
Synonyms:
ACT, ACTG, DFNA20, DFNA26, HEL-176, actin, cytoplasmic 2, cytoskeletal gamma-actin, epididymis luminal protein 176
Genomic Location:
Chr 17: 77091594-77094422
Description:
Actins are highly conserved proteins that are involved in various types of cell motility and in maintenance of the cytoskeleton. Three main groups of actin isoforms have been identified in vertebrate animals: alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and g...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Schizosaccharomyces pombe Bos taurus Gallus gallus Canis lupus familiaris Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 17
17q25.3


Transcripts Names
NM_001614
NM_001199954
NR_037688
Protein Names
A8K7C2
P63261
Q5U032
Q96E67



GO Molecular Function

structural molecule activity | enzyme binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | ATP binding | ubiquitin-like protein ligase binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | ubiquitin protein ligase binding | structural constituent of cytoskeleton | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | profilin binding | small molecule binding

GO Biological Process

positive regulation of immune response | actin filament-based process | response to cytokine | immune response-regulating signaling pathway | actin cytoskeleton organization | establishment of localization | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | cell differentiation | immune response-activating cell surface receptor signaling pathway | striated muscle cell development | defense response | membrane organization | tissue homeostasis | cellular process | Fc-gamma receptor signaling pathway involved in phagocytosis | localization | sarcomere organization | hemostasis | muscle structure development | anatomical structure homeostasis | muscle cell differentiation | cell junction assembly | regulation of immune response | regulation of cellular process | ephrin receptor signaling pathway | cellular component organization | platelet aggregation | cellular response to interferon-gamma | response to stimulus | muscle cell development | positive regulation of immune system process | response to stress | multicellular organismal homeostasis | supramolecular fiber organization | immune response-activating signal transduction | cellular component assembly | blood coagulation | organelle assembly | wound healing | Fc-gamma receptor signaling pathway | platelet activation | enzyme linked receptor protein signaling pathway | vesicle-mediated transport | cellular response to cytokine stimulus | actomyosin structure organization | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis | cell communication | homeostatic process | striated muscle cell differentiation | coagulation | activation of immune response | response to organic substance | response to wounding | import into cell | anatomical structure development | structural constituent of cytoskeleton | cell surface receptor signaling pathway | regulation of body fluid levels | endocytosis | cell adhesion | immune response | retina homeostasis | myofibril assembly | cytoskeleton organization | cell-cell adhesion | response to interferon-gamma | cell activation | anatomical structure formation involved in morphogenesis | signaling | cell development | anatomical structure morphogenesis | developmental process | organelle organization | Fc receptor signaling pathway | Fc receptor mediated stimulatory signaling pathway | innate immune response | transmembrane receptor protein tyrosine kinase signaling pathway | immune system process | cellular response to organic substance | phagocytosis | homotypic cell-cell adhesion | signal transduction | multicellular organismal process

GO Cellular Component

supramolecular fiber | intracellular membrane-bounded organelle | adherens junction | focal adhesion | cytoplasmic vesicle | cell | myofibril | cytoplasm | cell-substrate junction | intracellular organelle | actin cytoskeleton | contractile fiber | protein-containing complex | plasma membrane | vesicle | extracellular exosome | filamentous actin | extracellular region | membrane-bounded organelle | extracellular vesicle | dense body | nucleus | organelle | extracellular space | cell periphery | cell-substrate adherens junction | blood microparticle | cytosol | intracellular vesicle | actin filament | cytoskeleton | endocytic vesicle | intracellular | cell junction | myelin sheath | membrane | supramolecular complex | phagocytic vesicle