Name: | Activin Receptors |
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Description: | Receptors for ACTIVINS are membrane protein kinases belonging to the family of PROTEIN-SERINE-THREONINE KINASES, thus also named activin receptor-like kinases (ALK's). Activin receptors also bind TRANSFORMING GROWTH FACTOR BETA. As those transmembrane receptors of the TGF-beta superfamily (RECEPTORS, TRANSFORMING GROWTH FACTOR BETA), ALK's consist of two different but related protein kinases, Type I and Type II. Activins initiate cellular signal transduction by first binding to the type II receptors (ACTIVIN RECEPTORS, TYPE II ) which then recruit and phosphorylate the type I receptors (ACTIVIN RECEPTORS, TYPE I ) with subsequent activation of the type I kinase activity. |
Synonyms: |
Activin Receptor-Like Kinases; Receptor-like Kinase, Activin; Activin Receptor like Kinase; Kinase, Activin Receptor-like; Activin Receptor like Kinases; Receptor, Activin; Receptor-like Kinases, Activin; Activin Receptor-like Kinase; Activin Receptor; Kinases, Activin Receptor-like
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