QuickView for Adh5 (gene)
- Gene Symbol:
- ADH5
Homo sapiens - Full name:
- alcohol dehydrogenase 5 (class III), chi polypeptide
- Synonyms:
- ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR, HEL-S-60p, alcohol dehydrogenase class-3, S-(hydroxymethyl)glutathione dehydrogenase, S-nitrosoglutathione reductase, alcohol dehydrogenase (class III), chi polypeptide, alcohol dehydrogenase class chi chain, alcohol dehydrogenase class-III, epididymis secretory sperm binding protein Li 60p, formaldehyde dehydrogenase, glutathione-dependent formaldehyde dehydrogenase
- Genomic Location:
- Chr 4: 100211152-100228954
- Description:
-
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity ...
- Orthologs:
- Mus musculus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Rattus norvegicus , Danio rerio , Schizosaccharomyces pombe , Gallus gallus , Bos taurus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
4q23
GO Molecular Function
fatty acid binding | oxidoreductase activity, acting on CH-OH group of donors | cation binding | carboxylic acid binding | lipid binding | catalytic activity | formaldehyde dehydrogenase activity | anion binding | electron transfer activity | identical protein binding | ion binding | alcohol dehydrogenase (NAD) activity | protein binding | protein homodimerization activity | zinc ion binding | aldehyde dehydrogenase (NAD) activity | protein dimerization activity | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | transition metal ion binding | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | organic acid binding | metal ion binding | oxidoreductase activity | S-(hydroxymethyl)glutathione dehydrogenase activity | small molecule binding
GO Biological Process
respiratory gaseous exchange | oxidoreductase activity, acting on CH-OH group of donors | response to lipopolysaccharide | peptidyl-amino acid modification | generation of precursor metabolites and energy | cellular detoxification of aldehyde | cellular process | organic substance catabolic process | cellular detoxification | ethanol metabolic process | catabolic process | cellular lipid metabolic process | response to stimulus | positive regulation of blood pressure | response to stress | alcohol metabolic process | electron transport chain | response to molecule of bacterial origin | cellular response to toxic substance | blood circulation | protein modification process | macromolecule modification | organic hydroxy compound metabolic process | retinoid metabolic process | response to external biotic stimulus | nitrogen compound metabolic process | respiratory system process | antibiotic metabolic process | formaldehyde dehydrogenase activity | lipid metabolic process | response to nitrosative stress | electron transfer activity | response to lipid | regulation of blood pressure | small molecule metabolic process | response to toxic substance | formaldehyde metabolic process | response to bacterium | ethanol oxidation | alcohol dehydrogenase (NAD) activity | drug metabolic process | cellular aldehyde metabolic process | protein metabolic process | response to organic substance | peptidyl-cysteine S-nitrosylation | aldehyde dehydrogenase (NAD) activity | metabolic process | oxidation-reduction process | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | organic substance metabolic process | diterpenoid metabolic process | protein nitrosylation | cellular protein metabolic process | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | response to biotic stimulus | aldehyde catabolic process | isoprenoid metabolic process | cellular protein modification process | detoxification | formaldehyde catabolic process | cellular metabolic process | oxidoreductase activity | S-(hydroxymethyl)glutathione dehydrogenase activity | response to redox state | response to other organism | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | vesicle | extracellular exosome | mitochondrion | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cytosol | intracellular
