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QuickView for Ahsg (gene)


Gene Symbol:
AHSG Homo sapiens Homo sapiens
Full name:
alpha 2-HS glycoprotein
Synonyms:
A2HS, AHS, FETUA, HSGA, alpha-2-HS-glycoprotein, alpha-2-Z-globulin, ba-alpha-2-glycoprotein, fetuin-A
Genomic Location:
Chr 3: 187813544-187821801
Description:
The protein encoded by this gene is a negatively-charged serum glycoprotein that is synthesized by hepatocytes. The encoded protein consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several processes, including endocytosis, brain development, and the formation of bone tissue. ...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Gallus gallus Pan troglodytes Danio rerio Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 3
3q27.3





GO Molecular Function

endopeptidase inhibitor activity | kinase regulator activity | enzyme inhibitor activity | molecular function regulator | kinase inhibitor activity | peptidase inhibitor activity | enzyme regulator activity | cysteine-type endopeptidase inhibitor activity

GO Biological Process

negative regulation of phosphorylation | negative regulation of cellular response to insulin stimulus | endopeptidase inhibitor activity | exocytosis | positive regulation of cellular component organization | neutrophil activation | regulation of localization | establishment of localization | platelet degranulation | negative regulation of cellular process | defense response | negative regulation of proteolysis | cellular process | secretion | leukocyte degranulation | localization | negative regulation of signaling | kinase regulator activity | regulation of proteolysis | negative regulation of cellular metabolic process | regulation of bone mineralization | regulation of cellular process | leukocyte activation | regulation of metabolic process | negative regulation of biomineral tissue development | response to stimulus | enzyme inhibitor activity | neutrophil degranulation | response to stress | leukocyte activation involved in immune response | secretion by cell | regulation of phagocytosis | negative regulation of metabolic process | protein modification process | macromolecule modification | molecular function regulator | system development | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | multicellular organism development | negative regulation of catalytic activity | regulation of peptidase activity | leukocyte mediated immunity | regulation of catalytic activity | regulation of phosphorylation | pinocytosis | regulation of ossification | negative regulation of peptidase activity | regulation of nitrogen compound metabolic process | negative regulation of insulin receptor signaling pathway | vesicle-mediated transport | acute-phase response | regulation of cellular protein metabolic process | regulated exocytosis | regulation of cellular metabolic process | inflammatory response | cell activation involved in immune response | myeloid cell activation involved in immune response | regulation of protein metabolic process | neutrophil activation involved in immune response | positive regulation of transport | protein metabolic process | negative regulation of bone mineralization | kinase inhibitor activity | import into cell | negative regulation of ossification | anatomical structure development | metabolic process | regulation of vesicle-mediated transport | endocytosis | immune response | organic substance metabolic process | regulation of insulin receptor signaling pathway | negative regulation of cellular protein metabolic process | positive regulation of phagocytosis | regulation of cellular response to insulin stimulus | regulation of phosphate metabolic process | cell activation | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | regulation of endocytosis | peptidase inhibitor activity | cellular protein metabolic process | enzyme regulator activity | regulation of endopeptidase activity | regulation of developmental process | developmental process | cellular protein modification process | regulation of transport | neutrophil mediated immunity | negative regulation of hydrolase activity | ossification | acute inflammatory response | skeletal system development | immune system process | cellular metabolic process | cysteine-type endopeptidase inhibitor activity | regulation of inflammatory response | positive regulation of endocytosis | regulation of cellular component organization | regulation of signaling | negative regulation of endopeptidase activity | post-translational protein modification | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

secretory granule | intracellular membrane-bounded organelle | extracellular matrix | cytoplasmic vesicle | cell | cytoplasmic vesicle lumen | cytoplasm | collagen-containing extracellular matrix | intracellular organelle | endoplasmic reticulum | platelet alpha granule | Golgi apparatus | secretory vesicle | endomembrane system | vesicle | endoplasmic reticulum lumen | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | membrane-enclosed lumen | secretory granule lumen | blood microparticle | intracellular vesicle | intracellular | platelet alpha granule lumen | vesicle lumen