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QuickView for Aldehyde dehydrogenase 2 (gene)


Gene Symbol:
Aldh1a1 Rattus norvegicus Rattus norvegicus
Full name:
aldehyde dehydrogenase 1 family, member A1
Synonyms:
Ahd2, Aldh1, Aldh2, retinal dehydrogenase 1, ALDH-E1, ALHDII, RALDH 1, aldehyde dehydrogenase 1, subfamily A1, aldehyde dehydrogenase 1A1, aldehyde dehydrogenase 2, aldehyde dehydrogenase family 1 member A1, aldehyde dehydrogenase family 1, subfamily A1, aldehyde dehydrogenase, cytosolic, ralDH1
Genomic Location:
Chr 1: 223731675-223773285
Description:
ubiquitous enzyme located in virtually all mammalian tissues; catalyzes oxidation of aldehyde substrates to carboxylic acids; detoxifies ethanol-derived acetaldehyde
Orthologs:
Homo sapiens Mus musculus D. melanogaster Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_022407
Protein Names
P51647
O09184



GO Molecular Function

cofactor binding | nucleotide binding | coenzyme binding | catalytic activity | identical protein binding | organic cyclic compound binding | protein binding | retinal dehydrogenase activity | benzaldehyde dehydrogenase (NAD+) activity | aldehyde dehydrogenase (NAD) activity | NAD binding | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | heterocyclic compound binding | oxidoreductase activity | 3-chloroallyl aldehyde dehydrogenase activity | small molecule binding

GO Biological Process

protein homooligomerization | positive regulation of apoptotic process | morphogenesis of an epithelium | isoprenoid biosynthetic process | regulation of programmed cell death | eye development | response to hormone | embryonic camera-type eye morphogenesis | response to drug | response to antibiotic | cellular process | response to estradiol | optic cup morphogenesis involved in camera-type eye development | multicellular organismal reproductive process | terpenoid biosynthetic process | tissue development | regulation of cellular process | regulation of apoptotic process | retinoic acid biosynthetic process | hepaticobiliary system development | epithelium development | cellular component organization | cellular lipid metabolic process | urogenital system development | response to stimulus | monocarboxylic acid metabolic process | midgut development | response to stress | alcohol metabolic process | ovulation cycle | reproduction | response to alcohol | retinol metabolic process | rhythmic process | cellular component assembly | cellular biosynthetic process | kidney development | embryo development | response to ethanol | organic hydroxy compound metabolic process | retinoid metabolic process | system development | reproductive process | multicellular organism development | protein complex oligomerization | lipid metabolic process | regulation of hormone levels | response to lipid | 9-cis-retinoic acid biosynthetic process | animal organ morphogenesis | liver development | small molecule metabolic process | protein homotetramerization | response to oxidative stress | embryonic camera-type eye development | biosynthetic process | digestive tract development | lipid biosynthetic process | protein tetramerization | response to toxic substance | sensory organ development | eye morphogenesis | retinoic acid metabolic process | renal system development | response to retinoic acid | embryonic morphogenesis | drug metabolic process | carboxylic acid metabolic process | multicellular organism reproduction | embryonic organ morphogenesis | protein-containing complex assembly | response to organic substance | gland development | tissue morphogenesis | digestive system development | retinal dehydrogenase activity | benzaldehyde dehydrogenase (NAD+) activity | aldehyde dehydrogenase (NAD) activity | anatomical structure development | metabolic process | oxidation-reduction process | embryonic organ development | 9-cis-retinoic acid metabolic process | positive regulation of cell death | morphogenesis of embryonic epithelium | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | embryonic camera-type eye formation | organic substance metabolic process | animal organ development | positive regulation of programmed cell death | diterpenoid metabolic process | camera-type eye development | anatomical structure formation involved in morphogenesis | estrous cycle | response to organic cyclic compound | organic acid metabolic process | hormone metabolic process | anatomical structure morphogenesis | camera-type eye morphogenesis | isoprenoid metabolic process | developmental process | tube development | cellular metabolic process | embryonic eye morphogenesis | regulation of cell death | oxidoreductase activity | 3-chloroallyl aldehyde dehydrogenase activity | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | cytosol | intracellular