Name: | Aldosterone |
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PubChem Compound ID: | 11987810 |
Description: | A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium. |
Molecular formula: | C21H28O5 |
Molecular weight: | 360.444 g/mol |
Synonyms: |
As4
|
Name: | Aldosterone |
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Name (isomeric): | DB04630 |
Drug Type: | small molecule |
Description: | A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium. |
Synonyms: |
Aldocortene; Aldocorten; Aldosterona [inn-spanish]; 11beta,21-Dihydroxy-3,20-diketopregn-4-ene-18-al; 11beta,21-dihydroxy-3,20-dioxo-4-pregnen-18-al; Aldocortin; 18-Formyl-11beta,21-dihydroxy-4-pregnene-3,20-dione; 18-Aldocorticosterone; Aldosteronum [inn-latin]; 18-Oxocorticosterone.
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CAS number: | 52-39-1 |
Pharmacology: |
At the late distal tubule and collecting duct, aldosterone has two main actions: 1) aldosterone acts on mineralocorticoid receptors (MR) on principal cells in the distal tubule of the kidney nephron, increasing the permeability of their apical (luminal) membrane to potassium and sodium and activates their basolateral Na+/K+ pumps, stimulating ATP h...
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Affected organisms: | Humans and other mammals |