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QuickView for Alverine (compound)


PubChem
Name: alverine
PubChem Compound ID: 21718
Molecular formula: C26H35NO7
Molecular weight: 473.559 g/mol
Synonyms:
Dipropylamine, N-ethyl-3, 3'-diphenyl-, citrate; CAS-5560-59-8; Alverine dihydrogen citrate; Alverine citrate; Spacolin; Alverine citrate salt; 150-59-4; Alverine citrate [USAN]; Dipropylamine, N-ethyl-3,3'-diphenyl-, citrate (1:1) (8CI); Dipropylamine, N-ethyl-3,3'-diphenyl-, citrate (1:1).
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DrugBank
Identification
Name: alverine
Name (isomeric): DB01616
Drug Type: small molecule
Synonyms:
Di(phenylpropyl)ethylamine; N,N-Bis(3-phenylpropyl)ethylamine; N-Ethyl-3,3'-diphenyldipropylamine; Alverine citrate; Alverina [inn-spanish]; Alverinum [inn-latin]; Phenpropamine; N-Ethyl-bis(3-phenylpropyl)amin; N-Ethyl-N-(3-phenylpropyl)benzenepropanamine; N-Ethyl-3-phenyl-N-(3-phenylpropyl)-1-propanamine.
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Brand: Dipropyline, Gamatran citrate, Dipropylin, Spasmaverine, Antispasmin, Profenil, Spacolin, Sestron
Category: Antispasmodics
CAS number: 5982-87-6
Pharmacology
Indication: Used to relieve cramps or spasms of the stomach and intestines. It is also useful in treating irritable bowel syndrome (IBS) and similar conditions. It can also be used to help relieve period pain. Alverine citrate is also under investigation to increase the cytotoxic effects of the proteasome inhibitor MG132 on breast cancer cells.
Pharmacology:
Alverine is a smooth muscle relaxant. Smooth muscle is a type of muscle that is not under voluntary control; it is the muscle present in places such as the gut and uterus. Alverine acts directly on the muscle in the gut, causing it to relax. This prevents the muscle spasms which occur in the gut in conditions such as irritable bowel syndrome and di...
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Affected organisms: Humans and other mammals
Interactions
Drug interaction:
DonepezilPossible antagonism of action
GalantaminePossible antagonism of action

Targets