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QuickView for Anxa5 (gene)


Gene Symbol:
ANXA5 Homo sapiens Homo sapiens
Full name:
annexin A5
Synonyms:
ANX5, ENX2, HEL-S-7, PP4, RPRGL3, annexin A5, CBP-I, PAP-I, VAC-alpha, anchorin CII, annexin V, annexin-5, calphobindin I, endonexin II, epididymis secretory protein Li 7, lipocortin V, placental anticoagulant protein 4, placental anticoagulant protein I, thromboplastin inhibitor, vascular anticoagulant-alpha
Genomic Location:
Chr 4: 122808598-122837626
Description:
The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellu...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 4
4q27





GO Molecular Function

kinase binding | ATPase activity, coupled to transmembrane movement of substances | peptide binding | peptide hormone binding | cation binding | protein kinase binding | ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism | receptor tyrosine kinase binding | enzyme binding | transmembrane transporter activity | lipid binding | enzyme inhibitor activity | signaling receptor binding | hydrolase activity | carbohydrate derivative binding | phospholipid binding | ATPase activity | pyrophosphatase activity | molecular function regulator | catalytic activity | anion binding | nucleoside-triphosphatase activity | cation transmembrane transporter activity | ATPase activity, coupled | cation-transporting ATPase activity | amide binding | active transmembrane transporter activity | lipase inhibitor activity | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | ion binding | protein tyrosine kinase binding | heparin binding | molecular adaptor activity | hormone binding | protein binding | calcium-transporting ATPase activity | metal ion transmembrane transporter activity | hydrolase activity, acting on acid anhydrides | glycosaminoglycan binding | calcium ion binding | phospholipase inhibitor activity | ATPase coupled ion transmembrane transporter activity | inorganic cation transmembrane transporter activity | enzyme regulator activity | calcium-dependent phospholipid binding | metal ion binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

GO Biological Process

ATP hydrolysis coupled cation transmembrane transport | protein homooligomerization | exocytosis | negative regulation of peptide secretion | positive regulation of apoptotic process | regulation of localization | regulation of programmed cell death | ATPase activity, coupled to transmembrane movement of substances | establishment of localization | response to hormone | platelet degranulation | negative regulation of cellular process | response to metal ion | negative regulation of protein secretion | regulation of peptide hormone secretion | cellular process | secretion | regulation of cell motility | localization | negative regulation of signaling | metal ion transport | hemostasis | negative regulation of apoptotic process | negative regulation of secretion | negative regulation of hormone secretion | response to inorganic substance | ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism | negative regulation of establishment of protein localization | response to peptide hormone | negative regulation of wound healing | regulation of cellular process | regulation of apoptotic process | transmembrane transporter activity | cellular response to organonitrogen compound | cellular component organization | cellular response to metal ion | regulation of peptide secretion | response to stimulus | enzyme inhibitor activity | negative regulation of protein transport | response to gonadotropin-releasing hormone | ATP hydrolysis coupled transmembrane transport | response to stress | response to peptide | cellular response to inorganic substance | divalent metal ion transport | secretion by cell | negative regulation of transport | regulation of protein transport | cellular component assembly | regulation of wound healing | regulation of peptide transport | molecular function regulator | blood coagulation | response to nitrogen compound | cellular response to hormone stimulus | cellular response to gonadotropin-releasing hormone | negative regulation of secretion by cell | negative regulation of catalytic activity | cellular response to peptide hormone stimulus | calcium ion transmembrane transport | protein complex oligomerization | regulation of catalytic activity | ATP hydrolysis coupled ion transmembrane transport | regulation of hormone levels | ion transmembrane transport | regulation of hormone secretion | wound healing | regulation of flagellated sperm motility | cellular response to peptide | cation transmembrane transporter activity | cation-transporting ATPase activity | regulation of blood coagulation | active transmembrane transporter activity | lipase inhibitor activity | vesicle-mediated transport | cellular response to lead ion | regulation of cellular component movement | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | negative regulation of sequestering of calcium ion | negative regulation of peptide hormone secretion | regulated exocytosis | negative regulation of response to wounding | cell communication | regulation of locomotion | coagulation | cation transmembrane transport | protein-containing complex assembly | calcium-transporting ATPase activity | regulation of establishment of protein localization | response to organic substance | response to wounding | metal ion transmembrane transporter activity | regulation of body fluid levels | negative regulation of programmed cell death | calcium ion transport | regulation of secretion | positive regulation of cell death | regulation of sequestering of calcium ion | regulation of protein secretion | positive regulation of programmed cell death | inorganic cation transmembrane transport | regulation of response to wounding | regulation of cell communication | phospholipase inhibitor activity | ATPase coupled ion transmembrane transporter activity | negative regulation of molecular function | negative regulation of prolactin secretion | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | enzyme regulator activity | cation transport | response to thyroid hormone | negative regulation of coagulation | regulation of transport | response to organonitrogen compound | response to lead ion | response to calcium ion | negative regulation of blood coagulation | ion transport | cellular response to organic substance | regulation of protein localization | regulation of cell death | negative regulation of cell death | signal transduction | regulation of signaling | multicellular organismal process

GO Cellular Component

adherens junction | focal adhesion | cell | endothelial microparticle | external side of plasma membrane | cytoplasm | cell-substrate junction | plasma membrane | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cell periphery | cell-substrate adherens junction | blood microparticle | cytosol | cell surface | intracellular | cell junction | membrane