Name: | apramycin |
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PubChem Compound ID: | 10098771 |
Molecular formula: | C21H41N5O11 |
Molecular weight: | 539.577 g/mol |
Name: | apramycin |
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Name (isomeric): | DB04626 |
Drug Type: | small molecule |
Synonyms: |
Nebramycin II
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Category: | Antibacterial Agents |
CAS number: | 37321-09-8 |
Indication: | For the treatment of bacterial infections in animals. |
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Mechanism of Action: |
Apramycin stands out among aminoglycosides for its mechanism of action which is based on blocking translocation and its ability to bind also to the eukaryotic decoding site despite differences in key residues required for apramycin recognition by the bacterial target. The drug binds in the deep groove of the RNA which forms a continuously stacked h...
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Affected organisms: | Enteric bacteria and other eubacteria |
Drug interaction: |
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