QuickView for ArhGAP29 (gene)

Gene Symbol:

ARHGAP29 Homo sapiens

Full name:

Rho GTPase activating protein 29

Synonyms:

PARG1, rho GTPase-activating protein 29, PTPL1-associated RhoGAP 1 (PARG1), PTPL1-associated RhoGAP protein 1, rho-type GTPase-activating protein 29

Genomic Location:

Chr 1: 94407051-94475895

Description:

Rap1 is a small GTPase that, through effectors, regulates Rho GTPase signaling. These effectors- Rasip1, Radil, and the protein encoded by this gene- translocate to the cell membrane, where they form a multiprotein complex. This complex is necessary for Rap1-induced inhibition of Rho signaling. Defects in this gene may be a cause of nonsyndromic cl...

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Rap1 is a small GTPase that, through effectors, regulates Rho GTPase signaling. These effectors- Rasip1, Radil, and the protein encoded by this gene- translocate to the cell membrane, where they form a multiprotein complex. This complex is necessary for Rap1-induced inhibition of Rho signaling. Defects in this gene may be a cause of nonsyndromic cleft lip with or without cleft palate.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  AAAGGGA_MIR204_MIR211 ,  YATTNATC_UNKNOWN ,  TEF1_Q6 ,  RFX1_02 ,  GACAGGG_MIR339 ,  WGGAATGY_TEF1_Q6 ,  IK3_01 ,  KMCATNNWGGA_UNKNOWN ,  TGCACTT_MIR519C_MIR519B_MIR519A ,  ACCATTT_MIR522

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-145 ,  Predicted Gene Targets for miR-199 ,  Predicted Gene Targets for miR-204 ,  Predicted Gene Targets for miR-339 ,  Predicted Gene Targets for miR-377 ,  Predicted Gene Targets for miR-93

miRNA binding sites
(Source: miRecords):

hsa-miR-1 Targeted Genes ,  hsa-miR-124 Targeted Genes

Cytogenetic Map:

1p22.1

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