QuickView for B3GNT3;jsessionid=7D29A8820CE63C1EE5AFBA827D143A08 (gene)

Gene Symbol:

B3GNT3 Homo sapiens

Full name:

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3

Synonyms:

B3GAL-T8, B3GN-T3, B3GNT-3, HP10328, TMEM3, beta3Gn-T3, N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3, UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 8, UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 8, beta-1,3-GalTase 8, beta-1,3-Gn-T3, beta-1,3-N-acetylglucosaminyltransferase bGnT-3, beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase, beta-3-Gx-T8, beta3GalT8, core 1 extending beta-1,3-N-acetylglucosaminyltransferase, core1-beta3GlcNAcT, putative type II membrane protein, transmembrane protein 3

Genomic Location:

Chr 19: 17766919-17785385

Description:

This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the ...

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This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Cytogenetic Map:

19p13.11

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