QuickView for BAG1 (gene)
- Gene Symbol:
- BAG1
Homo sapiens - Full name:
- BCL2 associated athanogene 1
- Synonyms:
- BAG-1, HAP, RAP46, BAG family molecular chaperone regulator 1, BCL2-associated athanogene, Bcl-2 associating athanogene-1 protein, Bcl-2-binding protein, glucocortoid receptor-associated protein RAP46, receptor-associated protein, 46-KD
- Genomic Location:
- Chr 9: 33242469-33254761
- Description:
-
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Mu...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
9p13.3
GO Molecular Function
enzyme binding | nucleotide binding | molecular function regulator | chaperone binding | ubiquitin-like protein ligase binding | adenyl nucleotide binding | purine nucleotide binding | organic cyclic compound binding | protein binding | ubiquitin protein ligase binding | enzyme regulator activity | adenyl-nucleotide exchange factor activity | ATPase regulator activity | heterocyclic compound binding | small molecule binding
GO Biological Process
'de novo' posttranslational protein folding | regulation of programmed cell death | negative regulation of cellular process | cellular process | chaperone-mediated protein folding | negative regulation of apoptotic process | regulation of cellular process | regulation of apoptotic process | response to stimulus | regulation of cellular response to heat | programmed cell death | molecular function regulator | regulation of cellular response to stress | apoptotic process | regulation of catalytic activity | 'de novo' protein folding | cell communication | cell surface receptor signaling pathway | negative regulation of programmed cell death | protein folding | cell death | signaling | enzyme regulator activity | chaperone cofactor-dependent protein refolding | adenyl-nucleotide exchange factor activity | ATPase regulator activity | regulation of cell death | negative regulation of cell death | signal transduction
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | cytosol | intracellular
