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QuickView for BAG4 (gene)


Gene Symbol:
BAG4 Homo sapiens Homo sapiens
Full name:
BCL2 associated athanogene 4
Synonyms:
BAG-4, SODD, BAG family molecular chaperone regulator 4, bcl-2-associated athanogene 4, silencer of death domains
Genomic Location:
Chr 8: 38153263-38187694
Description:
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa famil...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Bos taurus Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 8
8p11.23


Transcripts Names
NM_004874
NM_001204878
Protein Names
B4E217
O95429
O95818



GO Molecular Function

enzyme binding | nucleic acid binding | nucleotide binding | molecular function regulator | chaperone binding | ubiquitin-like protein ligase binding | adenyl nucleotide binding | purine nucleotide binding | organic cyclic compound binding | protein binding | ubiquitin protein ligase binding | enzyme regulator activity | adenyl-nucleotide exchange factor activity | ATPase regulator activity | heterocyclic compound binding | small molecule binding | RNA binding

GO Biological Process

regulation of supramolecular fiber organization | negative regulation of intracellular transport | positive regulation of locomotion | regulation of dephosphorylation | regulation of intracellular protein transport | response to cytokine | positive regulation of cellular component organization | ruffle organization | protein localization to cell periphery | regulation of cellular localization | regulation of localization | regulation of programmed cell death | negative regulation of cellular process | regulation of phosphatase activity | cellular response to tumor necrosis factor | negative regulation of mitochondrion organization | negative regulation of protein targeting to mitochondrion | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | regulation of organelle organization | positive regulation of cellular component movement | regulation of actin polymerization or depolymerization | regulation of fibroblast migration | cellular process | positive regulation of actin filament polymerization | regulation of cell motility | localization | positive regulation of peptidyl-serine phosphorylation | macromolecule localization | negative regulation of apoptotic process | response to growth factor | positive regulation of nitrogen compound metabolic process | negative regulation of establishment of protein localization | negative regulation of cellular metabolic process | regulation of protein kinase B signaling | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | regulation of protein complex assembly | positive regulation of cellular protein metabolic process | negative regulation of phosphatase activity | cellular component organization | regulation of actin filament length | response to stimulus | negative regulation of protein transport | regulation of cellular protein localization | regulation of cellular response to heat | positive regulation of protein metabolic process | negative regulation of intracellular protein transport | positive regulation of actin filament bundle assembly | cellular localization | positive regulation of fibroblast migration | ruffle assembly | negative regulation of transport | regulation of protein transport | negative regulation of metabolic process | regulation of cellular component size | cellular component assembly | regulation of peptide transport | regulation of cell adhesion | regulation of intracellular transport | molecular function regulator | positive regulation of stress fiber assembly | regulation of cellular response to stress | regulation of signal transduction | positive regulation of organelle organization | negative regulation of phosphate metabolic process | regulation of actin cytoskeleton organization | negative regulation of catalytic activity | regulation of actin filament organization | positive regulation of protein kinase B signaling | regulation of catalytic activity | regulation of actomyosin structure organization | regulation of phosphorylation | negative regulation of cellular protein localization | protein localization to plasma membrane | protein localization to membrane | cell projection assembly | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | positive regulation of protein complex assembly | regulation of cellular component movement | positive regulation of cell migration | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | regulation of mitochondrion organization | cell communication | regulation of cellular metabolic process | regulation of actin filament polymerization | positive regulation of cytoskeleton organization | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | regulation of locomotion | cellular response to epidermal growth factor stimulus | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | regulation of intracellular signal transduction | cell surface receptor signaling pathway | cell projection organization | positive regulation of supramolecular fiber organization | negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity | regulation of protein targeting | negative regulation of programmed cell death | cellular protein localization | positive regulation of cellular component biogenesis | protein folding | tumor necrosis factor-mediated signaling pathway | regulation of phosphate metabolic process | response to epidermal growth factor | regulation of peptidyl-serine phosphorylation | regulation of stress fiber assembly | regulation of cell communication | negative regulation of molecular function | signaling | protein localization | positive regulation of phosphorylation | enzyme regulator activity | cellular macromolecule localization | regulation of actin filament bundle assembly | adenyl-nucleotide exchange factor activity | regulation of transport | ATPase regulator activity | positive regulation of protein polymerization | negative regulation of dephosphorylation | negative regulation of hydrolase activity | positive regulation of metabolic process | regulation of actin filament-based process | response to tumor necrosis factor | cellular response to organic substance | regulation of protein localization | regulation of cell death | positive regulation of cell motility | negative regulation of cell death | regulation of cellular component organization | regulation of cytoskeleton organization | positive regulation of signaling | signal transduction | regulation of signaling | cellular response to growth factor stimulus | negative regulation of establishment of protein localization to mitochondrion | regulation of protein targeting to mitochondrion | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | plasma membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | cytosol | intracellular | membrane