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QuickView for BCLAF1 (gene)


Gene Symbol:
BCLAF1 Homo sapiens Homo sapiens
Full name:
BCL2 associated transcription factor 1
Synonyms:
BTF, bK211L9.1, bcl-2-associated transcription factor 1, BCLAF1 and THRAP3 family member 1
Genomic Location:
Chr 6: 136619694-136652682
Description:
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in c...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 6
6q23.3





GO Molecular Function

nucleic acid binding | DNA binding | organic cyclic compound binding | protein binding | heterocyclic compound binding | RNA binding

GO Biological Process

RNA metabolic process | positive regulation of macromolecule biosynthetic process | response to cytokine | positive regulation of cellular component organization | positive regulation of apoptotic process | regulation of programmed cell death | negative regulation of cellular process | negative regulation of RNA biosynthetic process | positive regulation of intrinsic apoptotic signaling pathway | positive regulation of cellular biosynthetic process | cellular process | negative regulation of nucleic acid-templated transcription | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | regulation of protein complex assembly | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | positive regulation of response to DNA damage stimulus | response to stimulus | response to stress | cellular nitrogen compound biosynthetic process | programmed cell death | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | apoptotic process | nitrogen compound metabolic process | regulation of signal transduction | regulation of intrinsic apoptotic signaling pathway | regulation of gene expression | cellular response to stress | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | positive regulation of protein complex assembly | cellular response to cytokine stimulus | biosynthetic process | aromatic compound biosynthetic process | regulation of apoptotic signaling pathway | regulation of cellular metabolic process | positive regulation of signal transduction | regulation of RNA metabolic process | response to organic substance | regulation of intracellular signal transduction | metabolic process | regulation of DNA-templated transcription in response to stress | positive regulation of DNA-templated transcription, initiation | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | positive regulation of cell death | regulation of response to DNA damage stimulus | nucleobase-containing compound metabolic process | positive regulation of cellular component biogenesis | organic substance metabolic process | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | positive regulation of programmed cell death | transcription, DNA-templated | regulation of cell communication | cellular response to leukemia inhibitory factor | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | regulation of DNA-templated transcription, initiation | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | cellular response to organic substance | regulation of cell death | regulation of cellular component organization | positive regulation of apoptotic signaling pathway | positive regulation of signaling | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nuclear body | nucleoplasm | nuclear speck | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular