QuickView for BDH1 (gene)

Gene Symbol:

BDH1 Homo sapiens

Full name:

3-hydroxybutyrate dehydrogenase 1

Synonyms:

BDH, SDR9C1, D-beta-hydroxybutyrate dehydrogenase, mitochondrial, (R)-3-hydroxybutyrate dehydrogenase, 3-hydroxybutyrate dehydrogenase (heart, mitochondrial), 3-hydroxybutyrate dehydrogenase, type 1, short chain dehydrogenase/reductase family 9C member 1

Genomic Location:

Chr 3: 198721051-198784591

Description:

This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxyb...

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This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

HNF3ALPHA_Q6 ,  AAAYWAACM_HFH4_01 ,  HFH1_01 ,  HNF3_Q6 ,  FOXJ2_01 ,  GGGCGGR_SP1_Q6 ,  TGTTTGY_HNF3_Q6 ,  TTGTTT_FOXO4_01

Cytogenetic Map:

3q29

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