QuickView for BHMT (gene)
- Gene Symbol:
- BHMT
Homo sapiens - Full name:
- betaine--homocysteine S-methyltransferase
- Synonyms:
- BHMT1, HEL-S-61p, betaine--homocysteine S-methyltransferase 1, epididymis secretory sperm binding protein Li 61p
- Genomic Location:
- Chr 5: 78443360-78463869
- Description:
-
This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
5q14.1
GO Molecular Function
S-methyltransferase activity | cation binding | betaine-homocysteine S-methyltransferase activity | catalytic activity | ion binding | zinc ion binding | transferase activity | transition metal ion binding | methyltransferase activity | metal ion binding
GO Biological Process
sulfur compound metabolic process | cellular process | organic substance catabolic process | S-methyltransferase activity | betaine-homocysteine S-methyltransferase activity | sulfur amino acid biosynthetic process | L-methionine salvage | S-adenosylmethionine metabolic process | cellular amino acid metabolic process | cellular biogenic amine metabolic process | regulation of cellular process | regulation of metabolic process | catabolic process | choline metabolic process | regulation of sulfur amino acid metabolic process | cellular amino acid biosynthetic process | cellular nitrogen compound metabolic process | cofactor metabolic process | protein modification process | amine metabolic process | cellular biosynthetic process | macromolecule modification | regulation of neurotransmitter levels | sulfur amino acid metabolic process | nitrogen compound metabolic process | amine catabolic process | amino-acid betaine metabolic process | methylation | regulation of cellular amino acid metabolic process | regulation of nitrogen compound metabolic process | small molecule metabolic process | methionine metabolic process | neurotransmitter metabolic process | amino-acid betaine catabolic process | biosynthetic process | neurotransmitter catabolic process | cellular modified amino acid catabolic process | regulation of cellular metabolic process | regulation of homocysteine metabolic process | drug metabolic process | carboxylic acid metabolic process | protein metabolic process | choline catabolic process | methionine biosynthetic process | metabolic process | organic substance metabolic process | organonitrogen compound catabolic process | organic acid metabolic process | cellular protein metabolic process | protein methylation | regulation of cellular ketone metabolic process | methyltransferase activity | cellular protein modification process | cellular modified amino acid metabolic process | cellular biogenic amine catabolic process | cellular metabolic process | macromolecule metabolic process
GO Cellular Component
cell | cytoplasm | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cytosol | intracellular
