QuickView for BIF-1 (gene)

Gene Symbol:

SH3GLB1 Homo sapiens

Full name:

SH3 domain containing GRB2 like, endophilin B1

Synonyms:

Bif-1, CGI-61, PPP1R70, dJ612B15.2, endophilin-B1, Bax-interacting factor 1, SH3 domain-containing GRB2-like protein B1, SH3-containing protein SH3GLB1, SH3-domain GRB2 like endophilin B1, protein phosphatase 1, regulatory subunit 70, testicular tissue protein Li 172

Genomic Location:

Chr 1: 86942845-86986455

Description:

This gene encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. This protein may also be involved in maintaining mitochondrial morphology. Alternate splicing results in multip...

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This gene encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. This protein may also be involved in maintaining mitochondrial morphology. Alternate splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TTTTGAG_MIR373 ,  GAGACTG_MIR452 ,  SRY_01 ,  ACTGAAA_MIR30A3P_MIR30E3P ,  TTGTTT_FOXO4_01

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-30-3p ,  Predicted Gene Targets for miR-382 ,  Predicted Gene Targets for miR-410

Cytogenetic Map:

1p22.3

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