QuickView for BLIMP1 (gene)

Gene Symbol:

PRDM1 Homo sapiens

Full name:

PR/SET domain 1

Synonyms:

BLIMP1, PRDI-BF1, PR domain zinc finger protein 1, B-lymphocyte-induced maturation protein 1, BLIMP-1, PR domain 1, PR domain containing 1, with ZNF domain, PRDI-binding factor-1, beta-interferon gene positive-regulatory domain I binding factor

Genomic Location:

Chr 6: 106640888-106664506

Description:

This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been re...

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This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NFAT_Q4_01 ,  TGGAAA_NFAT_Q4_01 ,  FOXO1_02 ,  AACWWCAANK_UNKNOWN ,  RTAAACA_FREAC2_01 ,  HNF4ALPHA_Q6 ,  HNF3ALPHA_Q6 ,  AP1_C ,  TGANTCA_AP1_C ,  CEBPA_01 ,  OCT1_B ,  TTANTCA_UNKNOWN ,  FOXJ2_02 ,  RYTTCCTG_ETS2_B ,  AREB6_02 ,  FOX_Q2 ,  RSRFC4_01 ,  HFH3_01 ,  TGANNYRGCA_TCF11MAFG_01 ,  FOXO4_01 ,  YATGNWAAT_OCT_C ,  OCT_Q6 ,  YTATTTTNR_MEF2_02 ,  SRF_Q6 ,  CATTGTYY_SOX9_B1 ,  GCANCTGNY_MYOD_Q6 ,  AAAYWAACM_HFH4_01 ,  AACTGAC_MIR223 ,  HFH1_01 ,  EVI1_04 ,  RSRFC4_Q2 ,  TTTGTAG_MIR520D ,  IPF1_Q4 ,  AREB6_04 ,  WGTTNNNNNAAA_UNKNOWN ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  AP1_Q6 ,  HNF1_C ,  CTTTGA_LEF1_Q2 ,  GR_Q6_01 ,  GTGCAAA_MIR507 ,  GGGCATT_MIR365 ,  AAGCAAT_MIR137 ,  OCT1_Q5_01 ,  OCT_C ,  HNF4_DR1_Q3 ,  CTTTGTA_MIR524 ,  STAT_Q6 ,  HNF4_01 ,  TATAAA_TATA_01 ,  OCT1_Q6 ,  RGAANNTTC_HSF1_01 ,  NFE2_01 ,  AP1_Q6_01 ,  FOXO3_01 ,  CATGTAA_MIR496 ,  CEBP_01 ,  FREAC3_01 ,  CDX2_Q5 ,  STAT5B_01 ,  CAGGTG_E12_Q6 ,  DR1_Q3 ,  CTCAGGG_MIR125B_MIR125A ,  LHX3_01 ,  AP1FJ_Q2 ,  TATA_C ,  NKX62_Q2 ,  AR_01 ,  HNF3_Q6 ,  HNF4_Q6 ,  BACH2_01 ,  ATTCTTT_MIR186 ,  GCAAAAA_MIR129 ,  HNF3B_01 ,  ACCAAAG_MIR9 ,  FOXJ2_01 ,  TGCTGAY_UNKNOWN ,  PITX2_Q2 ,  LMO2COM_02 ,  YKACATTT_UNKNOWN ,  OCT1_03 ,  AAGWWRNYGGC_UNKNOWN ,  CTCTGGA_MIR520A_MIR525 ,  FOXO1_01 ,  CTTTAAR_UNKNOWN ,  GCM_Q2 ,  HFH4_01 ,  TGTTTGY_HNF3_Q6 ,  NRF2_Q4 ,  AP1_Q4 ,  YCATTAA_UNKNOWN ,  STAT_01 ,  AATGTGA_MIR23A_MIR23B ,  TTGCCAA_MIR182 ,  FREAC2_01 ,  ELK1_01 ,  TAATTA_CHX10_01 ,  TTGTTT_FOXO4_01 ,  GR_01 ,  WGGAATGY_TEF1_Q6 ,  CHOP_01 ,  CART1_01 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  IK2_01 ,  STAT5A_04 ,  MEF2_03 ,  YTAATTAA_LHX3_01 ,  IK1_01 ,  COUP_DR1_Q6 ,  CTGYNNCTYTAA_UNKNOWN ,  PAX_Q6 ,  TTCYNRGAA_STAT5B_01 ,  AP1_Q2 ,  TCCATTKW_UNKNOWN ,  TGACAGNY_MEIS1_01 ,  GRE_C ,  WCAANNNYCAG_UNKNOWN ,  STAT5A_01 ,  YWATTWNNRGCT_UNKNOWN ,  ER_Q6_01 ,  GCTNWTTGK_UNKNOWN ,  AACTTT_UNKNOWN ,  PAX4_03 ,  TTANWNANTGGM_UNKNOWN ,  YNGTTNNNATT_UNKNOWN ,  PPAR_DR1_Q2 ,  TGACATY_UNKNOWN ,  CCAWWNAAGG_SRF_Q4 ,  AP1_Q4_01 ,  HNF1_Q6 ,  CEBPGAMMA_Q6 ,  FREAC4_01 ,  FOXO4_02 ,  PAX4_01 ,  TATTATA_MIR374 ,  GGGTGGRR_PAX4_03 ,  TGASTMAGC_NFE2_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-99 ,  Predicted Gene Targets for miR-125 ,  Predicted Gene Targets for miR-129 ,  Predicted Gene Targets for miR-145 ,  Predicted Gene Targets for miR-186 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-223 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-24 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-365 ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-450 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-137 ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-363 ,  Predicted Gene Targets for miR-374 ,  Predicted Gene Targets for miR-496

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Cytogenetic Map:

6q21

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