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QuickView for BMPR1B;jsessionid=DF3FB09F3D48514796170E68146687DE (gene)


Gene Symbol:
BMPR1B Homo sapiens Homo sapiens
Full name:
bone morphogenetic protein receptor type 1B
Synonyms:
ALK-6, ALK6, AMDD, BDA1D, BDA2, CDw293, bone morphogenetic protein receptor type-1B, BMP type-1B receptor, BMPR-1B, activin receptor-like kinase 6, bone morphogenetic protein receptor, type IB, serine/threonine receptor kinase
Genomic Location:
Chr 4: 95898151-96295099
Description:
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of hetero...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Bos taurus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 4
4q22.3





GO Molecular Function

transforming growth factor beta-activated receptor activity | cation binding | transmembrane signaling receptor activity | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | transforming growth factor beta receptor activity, type I | growth factor binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | signaling receptor activity | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transmembrane receptor protein serine/threonine kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | SMAD binding | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

limb development | cell morphogenesis | positive regulation of macromolecule biosynthetic process | chondrocyte development | neuron projection morphogenesis | developmental process involved in reproduction | ovarian follicle development | positive regulation of apoptotic process | gonad development | regulation of programmed cell death | female gonad development | eye development | ovarian cumulus expansion | negative regulation of cellular process | positive regulation of developmental process | bone development | cell differentiation | defense response | nervous system development | transforming growth factor beta-activated receptor activity | positive regulation of biomineral tissue development | cell part morphogenesis | endochondral bone morphogenesis | neurogenesis | generation of neurons | pattern specification process | positive regulation of cellular biosynthetic process | cellular process | positive regulation of cartilage development | cell projection morphogenesis | limb morphogenesis | developmental growth | neuron development | reproductive system development | multicellular organismal reproductive process | axon guidance | response to growth factor | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors | positive regulation of nitrogen compound metabolic process | regulation of bone mineralization | positive regulation of chondrocyte differentiation | tissue development | regulation of cell differentiation | gamete generation | glycoprotein biosynthetic process | regulation of cellular process | regulation of osteoblast differentiation | regulation of apoptotic process | regulation of metabolic process | cellular component organization | response to transforming growth factor beta | development of primary sexual characteristics | response to stimulus | female gamete generation | cell morphogenesis involved in neuron differentiation | cartilage condensation | response to stress | neuron projection guidance | germ cell development | regulation of cell proliferation | ovulation cycle | proteoglycan metabolic process | protein serine/threonine kinase activity | development of primary female sexual characteristics | transforming growth factor beta receptor activity, type I | reproduction | rhythmic process | retinal ganglion cell axon guidance | carbohydrate derivative biosynthetic process | positive regulation of RNA biosynthetic process | protein modification process | cartilage development | cellular biosynthetic process | dorsal/ventral pattern formation | macromolecule modification | regulation of nucleic acid-templated transcription | locomotion | response to BMP | system development | chondrocyte differentiation | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | regulation of cartilage development | multicellular organism development | phosphorus metabolic process | antral ovarian follicle growth | negative regulation of chondrocyte proliferation | regulation of ossification | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | axon development | positive regulation of cellular metabolic process | animal organ morphogenesis | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | regulation of transcription by RNA polymerase II | oogenesis | axonogenesis | positive regulation of cell differentiation | biosynthetic process | positive regulation of ossification | phosphorylation | regulation of apoptotic signaling pathway | protein phosphorylation | cell morphogenesis involved in differentiation | phosphate-containing compound metabolic process | sensory organ development | ovulation cycle process | positive regulation of extrinsic apoptotic signaling pathway | cell communication | regulation of cellular metabolic process | transmembrane receptor protein serine/threonine kinase signaling pathway | skeletal system morphogenesis | inflammatory response | positive regulation of signal transduction | bone morphogenesis | regulation of RNA metabolic process | positive regulation of osteoblast differentiation | cellular response to transforming growth factor beta stimulus | neuron differentiation | multicellular organism reproduction | protein metabolic process | transmembrane receptor protein serine/threonine kinase activity | regionalization | response to organic substance | retina development in camera-type eye | anatomical structure development | cell surface receptor signaling pathway | cell projection organization | metabolic process | regulation of RNA biosynthetic process | positive regulation of cell death | regulation of chondrocyte differentiation | protein kinase activity | neuron projection development | organic substance metabolic process | connective tissue development | mammalian oogenesis stage | animal organ development | positive regulation of programmed cell death | camera-type eye development | transforming growth factor beta receptor signaling pathway | BMP signaling pathway | regulation of cell communication | regulation of extrinsic apoptotic signaling pathway via death domain receptors | signaling | regulation of transcription, DNA-templated | cell development | cellular protein metabolic process | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | reproductive structure development | regulation of developmental process | kinase activity | developmental process | cell aggregation | cellular protein modification process | carbohydrate derivative metabolic process | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | positive regulation of metabolic process | cellular response to BMP stimulus | skeletal system development | cellular metabolic process | female sex differentiation | cellular response to organic substance | regulation of cell death | sex differentiation | glycoprotein metabolic process | chemotaxis | sexual reproduction | positive regulation of bone mineralization | positive regulation of apoptotic signaling pathway | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | proteoglycan biosynthetic process | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

integral component of membrane | dendrite | neuron projection | somatodendritic compartment | cell body | cell | neuronal cell body | plasma membrane protein complex | HFE-transferrin receptor complex | intrinsic component of membrane | receptor complex | dendritic tree | protein-containing complex | cell projection | plasma membrane | integral component of plasma membrane | cell periphery | membrane | intrinsic component of plasma membrane