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QuickView for BNP (gene)

Gene Symbol:
NPPB Homo sapiens Homo sapiens
Full name:
natriuretic peptide B
BNP, natriuretic peptides B, brain type natriuretic peptide, gamma-brain natriuretic peptide, natriuretic peptide precursor B, natriuretic protein
Genomic Location:
Chr 1: 11840108-11841579
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone s...
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 1

Transcripts Names
Protein Names

GO Molecular Function

hormone receptor binding | signaling receptor binding | hormone activity | molecular function regulator | protein binding | receptor regulator activity | receptor ligand activity | diuretic hormone activity

GO Biological Process

purine ribonucleotide metabolic process | regulation of blood vessel diameter | cyclic nucleotide biosynthetic process | regulation of localization | establishment of localization | negative regulation of cellular process | regulation of renal sodium excretion | cellular process | secretion | localization | cGMP biosynthetic process | receptor guanylyl cyclase signaling pathway | nucleotide metabolic process | ribose phosphate metabolic process | purine nucleotide biosynthetic process | ribonucleotide metabolic process | regulation of angiogenesis | regulation of cellular process | organic cyclic compound metabolic process | positive regulation of renal sodium excretion | cellular aromatic compound metabolic process | regulation of urine volume | regulation of vasculature development | response to stimulus | purine nucleotide metabolic process | regulation of excretion | regulation of blood vessel size | cellular nitrogen compound biosynthetic process | cyclic purine nucleotide metabolic process | negative regulation of angiogenesis | cellular nitrogen compound metabolic process | hormone activity | carbohydrate derivative biosynthetic process | blood circulation | cellular biosynthetic process | molecular function regulator | nucleotide biosynthetic process | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of urine volume | negative regulation of growth | phosphorus metabolic process | cyclic nucleotide metabolic process | positive regulation of secretion | regulation of blood pressure | organophosphate metabolic process | enzyme linked receptor protein signaling pathway | small molecule metabolic process | regulation of vascular permeability | cGMP metabolic process | nucleobase-containing small molecule metabolic process | biosynthetic process | aromatic compound biosynthetic process | purine ribonucleotide biosynthetic process | phosphate-containing compound metabolic process | cell communication | regulation of tube size | positive regulation of transport | negative regulation of cell growth | regulation of signaling receptor activity | receptor regulator activity | regulation of growth | cell surface receptor signaling pathway | metabolic process | regulation of body fluid levels | regulation of tube diameter | regulation of secretion | body fluid secretion | receptor ligand activity | nucleobase-containing compound metabolic process | organic substance metabolic process | protein folding | renal system process | regulation of cell communication | signaling | ribose phosphate biosynthetic process | regulation of developmental process | regulation of cell growth | diuretic hormone activity | carbohydrate derivative metabolic process | regulation of transport | negative regulation of vasculature development | heterocycle metabolic process | cellular metabolic process | regulation of cellular component organization | signal transduction | regulation of signaling | multicellular organismal process

GO Cellular Component

protein-containing complex | extracellular region | extracellular space