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QuickView for BPP (gene)


Gene Symbol:
SRPX2 Homo sapiens Homo sapiens
Full name:
sushi repeat containing protein, X-linked 2
Synonyms:
BPP, CBPS, PMGX, RESDX, SRPUL, sushi repeat-containing protein SRPX2, sushi-repeat protein up-regulated in leukemia, sushi-repeat protein upregulated in leukemia
Genomic Location:
Chr X: 99785819-99812952
Description:
This gene encodes a secreted protein that contains three sushi repeat motifs. The encoded protein may play a role in the development of speech and language centers in the brain. This protein may also be involved in angiogenesis. Mutations in this gene are the cause of bilateral perisylvian polymicrogyria, rolandic epilepsy, speech dyspraxia and cog...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr X
Xq22.1


Transcripts Names
NM_014467
Protein Names
O60687
Q8WW85
B3KQT3



GO Molecular Function

signaling receptor binding | hepatocyte growth factor binding | growth factor binding | identical protein binding | protein binding

GO Biological Process

positive regulation of locomotion | positive regulation of cellular component organization | cell motility | regulation of synapse assembly | regulation of localization | positive regulation of developmental process | regulation of sprouting angiogenesis | positive regulation of cellular component movement | blood vessel morphogenesis | cellular process | regulation of cell motility | localization | regulation of angiogenesis | regulation of cellular process | regulation of metabolic process | positive regulation of epithelial cell migration | regulation of vasculature development | vasculature development | tube morphogenesis | cardiovascular system development | positive regulation of sprouting angiogenesis | positive regulation of blood vessel endothelial cell migration | regulation of synapse structure or activity | blood vessel development | locomotion | system development | multicellular organism development | regulation of phosphorylation | regulation of synapse organization | regulation of cell migration | regulation of cellular component movement | regulation of cell migration involved in sprouting angiogenesis | regulation of endothelial cell migration | positive regulation of cell migration | angiogenesis | regulation of cellular metabolic process | regulation of locomotion | positive regulation of synapse assembly | anatomical structure development | behavior | cell adhesion | vocalization behavior | positive regulation of cellular component biogenesis | regulation of phosphate metabolic process | cell-cell adhesion | positive regulation of endothelial cell migration | anatomical structure formation involved in morphogenesis | regulation of epithelial cell migration | regulation of blood vessel endothelial cell migration | positive regulation of cell migration involved in sprouting angiogenesis | anatomical structure morphogenesis | regulation of nervous system development | regulation of developmental process | developmental process | tube development | positive regulation of cell motility | circulatory system development | positive regulation of angiogenesis | regulation of cellular component organization | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

synapse | cell | synaptic membrane | cytoplasm | plasma membrane | extracellular region | extracellular space | cell periphery | excitatory synapse | cell surface | intracellular | cell junction | membrane