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QuickView for BRCA2;jsessionid=4743BD6FAA6C4B3AEABAF5593E96A0A2;jsessionid=0F15961085C3868D57BBBCB973333BC0 (gene)


Gene Symbol:
BRCA2 Canis lupus familiaris Canis lupus familiaris
Full name:
breast cancer 2, early onset
Synonyms:
N/A
Genomic Location:
Chr 25: 10719192-10782555
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_001006653
Protein Names
Q8MKI9



GO Molecular Function

N-acetyltransferase activity | transferase activity, transferring acyl groups other than amino-acyl groups | N-acyltransferase activity | enzyme binding | catalytic activity | transferase activity, transferring acyl groups | histone acetyltransferase activity | identical protein binding | peptide N-acetyltransferase activity | H4 histone acetyltransferase activity | protein binding | transferase activity | peptide-lysine-N-acetyltransferase activity | H3 histone acetyltransferase activity | protease binding | acetyltransferase activity | protein C-terminus binding

GO Biological Process

mitotic cytokinesis | brain development | response to radiation | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | telomere maintenance | developmental process involved in reproduction | intracellular signal transduction | gonad development | female gonad development | peptidyl-amino acid modification | response to X-ray | establishment of localization | mitotic recombination-dependent replication fork processing | negative regulation of cellular process | histone modification | cell differentiation | male gamete generation | nervous system development | intrinsic apoptotic signaling pathway in response to DNA damage | male meiotic nuclear division | histone H3 acetylation | regulation of DNA replication | negative regulation of DNA metabolic process | positive regulation of cellular biosynthetic process | cellular process | DNA-dependent DNA replication maintenance of fidelity | localization | chromatin organization | cell maturation | mitotic DNA replication maintenance of fidelity | developmental growth | reproductive system development | cell cycle DNA replication | cytoskeleton-dependent cytokinesis | immune system development | multicellular organismal reproductive process | macromolecule localization | inner cell mass cell proliferation | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | mitotic DNA replication | negative regulation of cellular metabolic process | gamete generation | anatomical structure homeostasis | intrinsic apoptotic signaling pathway | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | DNA-dependent DNA replication | cellular component organization | regulation of cell division | development of primary sexual characteristics | response to UV | head development | negative regulation of DNA replication | histone H4 acetylation | male meiosis I | response to stimulus | female gamete generation | response to stress | germ cell development | regulation of cell proliferation | regulation of mammary gland epithelial cell proliferation | programmed cell death | development of primary female sexual characteristics | reproduction | cellular localization | peptidyl-lysine acetylation | cellular nitrogen compound metabolic process | telomere organization | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | hemopoiesis | protein modification process | cellular biosynthetic process | embryo development | DNA recombination | macromolecule modification | DNA repair | regulation of nucleic acid-templated transcription | apoptotic process | response to light stimulus | system development | nitrogen compound metabolic process | reproductive process | DNA damage response, signal transduction by p53 class mediator | replication fork processing | multicellular organism development | protein acetylation | cellular response to DNA damage stimulus | oocyte differentiation | histone acetyltransferase activity | DNA damage response, signal transduction resulting in transcription | positive regulation of cell cycle | positive regulation of mitotic cell cycle | signal transduction in response to DNA damage | regulation of gene expression | cellular response to stress | cell cycle | positive regulation of cellular metabolic process | establishment of protein localization to chromosome | regulation of nitrogen compound metabolic process | oogenesis | protein localization to organelle | negative regulation of mammary gland epithelial cell proliferation | cell proliferation | histone acetylation | internal peptidyl-lysine acetylation | biosynthetic process | cell division | cytokinesis | regulation of DNA-dependent DNA replication | response to gamma radiation | chordate embryonic development | cell communication | regulation of cellular metabolic process | regulation of cytokinesis | homeostatic process | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | H4 histone acetyltransferase activity | apoptotic signaling pathway | cell aging | regulation of mitotic cell cycle | multicellular organism reproduction | negative regulation of epithelial cell proliferation | protein metabolic process | negative regulation of DNA-dependent DNA replication | protein localization to chromosome, telomeric region | DNA metabolic process | establishment of protein localization to organelle | anatomical structure development | mitotic cell cycle | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | nuclear division | metabolic process | nucleotide-excision repair | regulation of RNA biosynthetic process | developmental maturation | cellular protein localization | peptidyl-lysine modification | nucleobase-containing compound metabolic process | organic substance metabolic process | cell death | negative regulation of biosynthetic process | animal organ development | mitotic recombination | replication fork protection | telomere maintenance via recombination | intrinsic apoptotic signaling pathway by p53 class mediator | establishment of protein localization | blastocyst development | meiosis I | oocyte development | meiotic cell cycle | establishment of protein localization to telomere | signaling | covalent chromatin modification | regulation of transcription, DNA-templated | response to UV-C | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | cell development | internal protein amino acid acetylation | protein localization | regulation of epithelial cell proliferation | H3 histone acetyltransferase activity | cellular protein metabolic process | cellular macromolecule localization | cellular macromolecule biosynthetic process | reproductive structure development | nuclear DNA replication | regulation of developmental process | developmental process | organelle organization | spermatogenesis | blastocyst growth | cellular protein modification process | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | oocyte maturation | heterocycle metabolic process | central nervous system development | in utero embryonic development | positive regulation of metabolic process | chromosome organization | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | female sex differentiation | sex differentiation | signal transduction by p53 class mediator | DNA replication | aging | sexual reproduction | response to ionizing radiation | protein localization to chromosome | signal transduction | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

condensed nuclear chromosome | secretory granule | lateral element | chromosome | intracellular membrane-bounded organelle | cytoplasmic vesicle | cell | nuclear lumen | synaptonemal complex | cytoplasm | BRCA2-MAGE-D1 complex | intracellular organelle | protein-containing complex | secretory vesicle | endomembrane system | nucleoplasm | nuclear chromosome | vesicle | chromosome, telomeric region | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular vesicle | nuclear chromosome, telomeric region | intracellular | condensed chromosome