QuickView for Baf170 (gene)
- Gene Symbol:
- SMARCC2
Homo sapiens - Full name:
- SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
- Synonyms:
- BAF170, CRACC2, Rsc8, SWI/SNF complex subunit SMARCC2, SWI/SNF complex 170 kDa subunit, SWI3-like protein, chromatin remodeling complex BAF170 subunit, mammalian chromatin remodeling complex BRG1-associated factor 170
- Genomic Location:
- Chr 12: 54843379-54869544
- Description:
-
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and ...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Schizosaccharomyces pombe , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
12q13.2
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | enhancer binding | nucleosome binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | protein-containing complex binding | chromatin binding | enhancer sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | nucleosomal DNA binding | organic cyclic compound binding | transcription coactivator activity | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | DNA-binding transcription factor activity | chromatin DNA binding | RNA polymerase II regulatory region sequence-specific DNA binding | RNA polymerase II distal enhancer sequence-specific DNA binding | transcription coregulator activity | heterocyclic compound binding
GO Biological Process
RNA metabolic process | positive regulation of macromolecule biosynthetic process | nucleosome organization | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of RNA biosynthetic process | nervous system development | positive regulation of cellular biosynthetic process | cellular process | chromatin organization | protein-DNA complex disassembly | negative regulation of nucleic acid-templated transcription | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nucleosome disassembly | system development | nitrogen compound metabolic process | multicellular organism development | ATP-dependent chromatin remodeling | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | chromatin remodeling | transcription coactivator activity | regulation of RNA metabolic process | DNA-binding transcription factor activity | chromatin assembly or disassembly | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | transcription, DNA-templated | regulation of transcription, DNA-templated | protein-containing complex disassembly | cellular macromolecule biosynthetic process | developmental process | organelle organization | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | heterocycle metabolic process | positive regulation of metabolic process | chromosome organization | cellular metabolic process | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
chromosome | intracellular membrane-bounded organelle | catalytic complex | cell | nuclear lumen | intracellular organelle | protein-containing complex | nucleoplasm | chromatin | nuclear chromosome | npBAF complex | membrane-bounded organelle | transcriptional repressor complex | nucleus | organelle | SWI/SNF superfamily-type complex | nBAF complex | membrane-enclosed lumen | nuclear chromatin | ATPase complex | SWI/SNF complex | intracellular
