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QuickView for Bglap2 (gene)


Gene Symbol:
Bglap2 Mus musculus Mus musculus
Full name:
bone gamma-carboxyglutamate protein 2
Synonyms:
BGP2, Bglap1, Bgp, Og2, mOC-B, osteocalcin-2, bone Gla protein 2, gamma-carboxyglutamic acid-containing protein 2, osteocalcin
Genomic Location:
Chr 3: 88181658-88182621
Description:
This gene encodes a preproprotein that is proteolytically processed to generate a mature protein product. This protein product is a hormone that is secreted by osteoblasts and may function in bone remodeling and energy metabolism. Homozygous knockout mice for this gene exhibit a gradual increase in bone size, density and strength, as well as elevat...
External Links:
Entrez Gene


Transcripts Names
NM_001032298
Protein Names
P86547
P04641



GO Molecular Function

structural molecule activity | cation binding | hydroxyapatite binding | ion binding | structural constituent of bone | calcium ion binding | metal ion binding

GO Biological Process

type B pancreatic cell proliferation | regulation of localization | response to hormone | bone development | cell differentiation | glucose homeostasis | regulation of peptide hormone secretion | positive regulation of protein secretion | cellular process | organic substance catabolic process | regulation of bone mineralization | response to peptide hormone | tissue development | regulation of cellular process | catabolic process | cellular response to organonitrogen compound | cellular lipid metabolic process | regulation of peptide secretion | response to stimulus | regulation of insulin secretion | response to peptide | positive regulation of hormone secretion | regulation of protein transport | regulation of peptide transport | positive regulation of peptide secretion | response to nitrogen compound | cellular response to hormone stimulus | system development | multicellular organism development | cellular response to peptide hormone stimulus | cellular response to insulin stimulus | lipid metabolic process | regulation of hormone levels | regulation of hormone secretion | regulation of ossification | pancreas development | positive regulation of secretion | cellular response to peptide | cell proliferation | cellular lipid catabolic process | homeostatic process | positive regulation of establishment of protein localization | positive regulation of transport | positive regulation of peptide hormone secretion | regulation of establishment of protein localization | response to organic substance | positive regulation of insulin secretion | epithelial cell proliferation | response to insulin | anatomical structure development | metabolic process | chemical homeostasis | regulation of secretion | lipid catabolic process | organic substance metabolic process | animal organ development | regulation of protein secretion | biomineral tissue development | positive regulation of protein transport | regulation of cell communication | regulation of developmental process | developmental process | regulation of transport | response to organonitrogen compound | ossification | osteoblast differentiation | skeletal system development | cellular metabolic process | cellular response to organic substance | regulation of protein localization | carbohydrate homeostasis | positive regulation of signaling | regulation of signaling | multicellular organismal process

GO Cellular Component

dendrite | intracellular membrane-bounded organelle | neuron projection | somatodendritic compartment | cell body | cell | neuronal cell body | cytoplasm | intracellular organelle | endoplasmic reticulum | dendritic tree | Golgi apparatus | cell projection | endomembrane system | perikaryon | vesicle | extracellular region | membrane-bounded organelle | organelle | extracellular space | rough endoplasmic reticulum | intracellular