QuickView for BimL (gene)
- Gene Symbol:
- Bcl2l11
Rattus norvegicus - Full name:
- BCL2 like 11
- Synonyms:
- Bim, BimL, Bod, bcl-2-like protein 11, BCL2-like 11 (apoptosis facilitator), Bcl-2 related apoptotic gene product BimL, bcl-2-related ovarian death protein, bcl2-L-11, bcl2-interacting mediator of cell death
- Genomic Location:
- Chr 3: 115692323-115722701
- Description:
-
proapototic Bcl-2 related protein that interacts with anti-apoptotic Bcl-2 family members to play a role in regulation of apoptosis
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
CHOP_01 , SOX9_B1 , HIF1_Q5 , AP2REP_01 , HIF1_Q3 , EGR_Q6 , AGCACTT_MIR93_MIR302A_MIR302B_MIR302C_MIR302D_MIR372_MIR373_MIR520E_MIR520A_MIR526B_MIR520B_MIR520C_MIR520D , GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D , TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P , GTGCAAT_MIR25_MIR32_MIR92_MIR363_MIR367
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-101 , Predicted Gene Targets for miR-144 , Predicted Gene Targets for miR-181 , Predicted Gene Targets for miR-20 , Predicted Gene Targets for miR-24 , Predicted Gene Targets for miR-25 , Predicted Gene Targets for miR-30 , Predicted Gene Targets for miR-9 , Predicted Gene Targets for miR-93 , Predicted Gene Targets for miR-376
GO Molecular Function
kinase binding | protein kinase binding | enzyme binding | protein-containing complex binding | cytoskeletal protein binding | dynein complex binding | protein heterodimerization activity | protein binding | protein dimerization activity | microtubule binding | tubulin binding
GO Biological Process
leukocyte homeostasis | positive regulation of cell killing | brain development | limb development | regulation of cysteine-type endopeptidase activity | response to virus | response to endoplasmic reticulum stress | positive regulation of cellular component organization | developmental process involved in reproduction | intracellular signal transduction | positive regulation of apoptotic process | cell-substrate adhesion | gonad development | regulation of programmed cell death | regulation of mitochondrial membrane permeability involved in apoptotic process | establishment of localization | positive regulation of mitochondrial membrane permeability involved in apoptotic process | embryonic appendage morphogenesis | male gamete generation | positive regulation of intrinsic apoptotic signaling pathway | nervous system development | intrinsic apoptotic signaling pathway in response to DNA damage | regulation of protein oligomerization | post-embryonic animal organ morphogenesis | regulation of organelle organization | positive regulation of fibroblast apoptotic process | membrane organization | regulation of neuron death | cellular process | localization | extrinsic apoptotic signaling pathway | limb morphogenesis | odontogenesis | reproductive system development | positive regulation of killing of cells of other organism | immune system development | multicellular organismal reproductive process | positive regulation of release of cytochrome c from mitochondria | regulation of proteolysis | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | gamete generation | interspecies interaction between organisms | intrinsic apoptotic signaling pathway | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | regulation of protein complex assembly | positive regulation of apoptotic process by virus | positive regulation of cellular protein metabolic process | cellular component organization | urogenital system development | development of primary sexual characteristics | head development | response to stimulus | thymus development | embryonic limb morphogenesis | modulation by virus of host process | positive regulation of protein metabolic process | positive regulation of peptidase activity | response to stress | tube morphogenesis | positive regulation of cysteine-type endopeptidase activity | programmed cell death | regulation of developmental pigmentation | reproduction | positive regulation of proteolysis | apoptotic mitochondrial changes | kidney development | embryo development | mitochondrion organization | positive regulation of membrane permeability | positive regulation of mitochondrion organization | myeloid cell homeostasis | apoptotic process | response to external biotic stimulus | system development | reproductive process | regulation of signal transduction | positive regulation of organelle organization | post-embryonic animal organ development | multicellular organism development | regulation of peptidase activity | mammary gland development | cellular response to DNA damage stimulus | spleen development | B cell apoptotic process | regulation of catalytic activity | regulation of killing of cells of other organism | regulation of intrinsic apoptotic signaling pathway | positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction | cellular process regulating host cell cycle in response to virus | positive regulation of cell cycle | cell killing | regulation of mitochondrial membrane permeability | cellular response to stress | modification of morphology or physiology of other organism | positive regulation of cellular metabolic process | animal organ morphogenesis | developmental pigmentation | mitochondrial transport | regulation of nitrogen compound metabolic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | post-embryonic animal morphogenesis | positive regulation of intracellular signal transduction | positive regulation of protein complex assembly | pigmentation | B cell homeostasis | positive regulation of hydrolase activity | homeostasis of number of cells | T cell apoptotic process | regulation of cellular protein metabolic process | positive regulation of endopeptidase activity | positive regulation of neuron death | regulation of apoptotic signaling pathway | post-embryonic development | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | sensory organ development | regulation of mitochondrion organization | mitochondrial membrane organization | chordate embryonic development | cell communication | regulation of cellular metabolic process | mitochondrial outer membrane permeabilization involved in programmed cell death | regulation of neuron apoptotic process | lymphocyte homeostasis | odontogenesis of dentin-containing tooth | regulation of protein metabolic process | positive regulation of signal transduction | apoptotic process involved in development | homeostatic process | embryo development ending in birth or egg hatching | renal system development | viral process | cellular response to virus | apoptotic signaling pathway | embryonic morphogenesis | positive regulation of molecular function | multicellular organism reproduction | development of primary male sexual characteristics | regulation of protein homooligomerization | regulation of growth | gland development | male sex differentiation | killing of cells of other organism | regulation of intracellular signal transduction | positive regulation of neuron apoptotic process | anatomical structure development | cell surface receptor signaling pathway | activation of cysteine-type endopeptidase activity involved in apoptotic process | male gonad development | ear development | positive regulation of cell death | cell adhesion | positive regulation of mitochondrial membrane permeability | positive regulation of cellular component biogenesis | cell death | animal organ development | positive regulation of programmed cell death | T cell homeostasis | anatomical structure formation involved in morphogenesis | regulation of cell communication | regulation of membrane permeability | signaling | cell-matrix adhesion | embryonic digit morphogenesis | positive regulation of protein homooligomerization | regulation of developmental growth | extrinsic apoptotic signaling pathway in absence of ligand | anatomical structure morphogenesis | regulation of endopeptidase activity | regulation of organ growth | response to biotic stimulus | reproductive structure development | regulation of developmental process | developmental process | organelle organization | spermatogenesis | tube development | modulation by virus of host morphology or physiology | positive regulation of protein oligomerization | regulation of fibroblast apoptotic process | tube formation | central nervous system development | in utero embryonic development | positive regulation of metabolic process | apoptotic process involved in morphogenesis | thymocyte apoptotic process | immune system process | hematopoietic or lymphoid organ development | regulation of cell death | sex differentiation | apoptotic process involved in embryonic digit morphogenesis | sexual reproduction | regulation of cellular component organization | positive regulation of apoptotic signaling pathway | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process
GO Cellular Component
supramolecular fiber | intracellular membrane-bounded organelle | extrinsic component of membrane | cell | BIM-BCL-2 complex | microtubule | cytoplasm | intracellular organelle | BIM-BCL-xl complex | protein-containing complex | microtubule cytoskeleton | mitochondrion | membrane-bounded organelle | organelle | cytosol | cytoskeleton | Bcl-2 family protein complex | intracellular | membrane | supramolecular complex
