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QuickView for Brahma (gene)


Gene Symbol:
Smarca2 Mus musculus Mus musculus
Full name:
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Synonyms:
2610209L14Rik, SNF2alpha, Snf2l2, brahma, brm, probable global transcription activator SNF2L2, ATP-dependent helicase SMARCA2, BAF190B, BRG1-associated factor 190B, SNF2-alpha, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2, protein brahma homolog, subunit of the SWI/SNF chromatin remodeling complex
Genomic Location:
Chr 19: 26679650-26852811
Orthologs:
Homo sapiens Rattus norvegicus Saccharomyces cerevisiae Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
AAAYRNCTG_UNKNOWN AACTTT_UNKNOWN MEF2_01 RSRFC4_01 CP2_01 CEBPA_01 CEBPB_02 TST1_01 OCT1_02 OCT1_04
miRNA binding sites
(Source: TargetScan):





GO Molecular Function

transcription regulatory region DNA binding | nucleic acid binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | chromatin binding | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | DNA binding | purine nucleotide binding | ion binding | organic cyclic compound binding | transcription coactivator activity | purine ribonucleoside triphosphate binding | protein binding | hydrolase activity, acting on acid anhydrides | histone binding | purine ribonucleotide binding | adenyl ribonucleotide binding | helicase activity | drug binding | transcription coregulator activity | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

RNA metabolic process | positive regulation of macromolecule biosynthetic process | nucleosome organization | smooth muscle cell differentiation | negative regulation of cellular process | negative regulation of RNA biosynthetic process | cell differentiation | aortic smooth muscle cell differentiation | nervous system development | positive regulation of cellular biosynthetic process | cellular process | chromatin organization | negative regulation of nucleic acid-templated transcription | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | muscle structure development | muscle cell differentiation | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | vasculature development | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | vascular smooth muscle cell differentiation | protein-DNA complex assembly | cardiovascular system development | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | cellular biosynthetic process | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | negative regulation of growth | multicellular organism development | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | cellular protein-containing complex assembly | regulation of cellular metabolic process | chromatin remodeling | transcription coactivator activity | regulation of RNA metabolic process | negative regulation of cell growth | protein-containing complex assembly | regulation of growth | chromatin assembly or disassembly | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | DNA packaging | transcription, DNA-templated | chromatin assembly | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | developmental process | organelle organization | regulation of cell growth | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | DNA conformation change | transcription coregulator activity | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | nucleosome assembly | positive regulation of metabolic process | chromosome organization | cellular metabolic process | circulatory system development | regulation of cellular component organization | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

chromosome | intracellular membrane-bounded organelle | catalytic complex | cell | nuclear lumen | intracellular organelle | intermediate filament cytoskeleton | protein-containing complex | nucleoplasm | chromatin | nuclear chromosome | npBAF complex | membrane-bounded organelle | nucleus | organelle | SWI/SNF superfamily-type complex | nBAF complex | membrane-enclosed lumen | nuclear chromatin | ATPase complex | SWI/SNF complex | cytoskeleton | intracellular