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QuickView for Brf2 (gene)


Gene Symbol:
BRF2 Homo sapiens Homo sapiens
Full name:
BRF2, RNA polymerase III transcription initiation factor subunit
Synonyms:
BRFU, TFIIIB50, transcription factor IIIB 50 kDa subunit, B-related factor 2, BRF-2, BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit, BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like, RNA polymerase III transcription initiation factor BRFU, hBRFU, hTFIIIB50, transcription factor IIB- related factor, TFIIIB50
Genomic Location:
Chr 8: 37820558-37826569
Description:
This gene encodes one of the multiple subunits of the RNA polymerase III transcription factor complex required for transcription of genes with promoter elements upstream of the initiation site. The product of this gene, a TFIIB-like factor, is directly recruited to the TATA-box of polymerase III small nuclear RNA gene promoters through its interact...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Danio rerio Bos taurus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 8
8p11.23


Transcripts Names
NM_018310



GO Molecular Function

transcription regulatory region DNA binding | cation binding | nucleic acid binding | DNA binding | ion binding | organic cyclic compound binding | RNA polymerase III regulatory region DNA binding | metal ion binding | heterocyclic compound binding | RNA polymerase III type 3 promoter DNA binding

GO Biological Process

RNA metabolic process | DNA-templated transcription, initiation | cellular process | regulation of transcription by RNA polymerase III | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | response to stimulus | response to stress | cellular nitrogen compound biosynthetic process | protein-DNA complex assembly | cellular nitrogen compound metabolic process | cellular component assembly | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | cellular response to oxidative stress | regulation of gene expression | cellular response to stress | regulation of nitrogen compound metabolic process | response to oxidative stress | biosynthetic process | aromatic compound biosynthetic process | cellular protein-containing complex assembly | DNA-templated transcriptional preinitiation complex assembly | regulation of cellular metabolic process | regulation of RNA metabolic process | protein-containing complex assembly | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | heterocycle metabolic process | cellular metabolic process | macromolecule metabolic process

GO Cellular Component

nuclear transcription factor complex | intracellular membrane-bounded organelle | cell | nuclear lumen | transcription factor complex | intracellular organelle | protein-containing complex | nucleoplasm | transcription factor TFIIIB complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular