QuickView for Brn3a (gene)

Gene Symbol:

POU4F1 Homo sapiens

Full name:

POU class 4 homeobox 1

Synonyms:

BRN3A, Oct-T1, RDC-1, brn-3A, POU domain, class 4, transcription factor 1, brain-3A, brain-specific homeobox/POU domain protein 3A, homeobox/POU domain protein RDC-1

Genomic Location:

Chr 13: 78071228-78075696

Description:

This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias.

This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  POU6F1_01 ,  TTTGCAC_MIR19A_MIR19B ,  TFIIA_Q6 ,  STAT4_01 ,  TTTGCAG_MIR518A2 ,  GCATTTG_MIR105 ,  AREB6_02 ,  RSRFC4_01 ,  E2F4DP1_01 ,  ZF5_01 ,  SMAD3_Q6 ,  AAANWWTGC_UNKNOWN ,  GGGACCA_MIR133A_MIR133B ,  CTATGCA_MIR153 ,  TMTCGCGANR_UNKNOWN ,  RSRFC4_Q2 ,  HP1SITEFACTOR_Q6 ,  CAGTGTT_MIR141_MIR200A ,  AREB6_04 ,  ATGTACA_MIR493 ,  TAGCTTT_MIR9 ,  TTGCACT_MIR130A_MIR301_MIR130B ,  E2A_Q2 ,  CTAWWWATA_RSRFC4_Q2 ,  WHN_B ,  WTGAAAT_UNKNOWN ,  GGGAGGRR_MAZ_Q6 ,  MEF2_02 ,  STAT_Q6 ,  TATAAA_TATA_01 ,  TAL1BETAE47_01 ,  RP58_01 ,  LFA1_Q6 ,  STAT5B_01 ,  CAGGTG_E12_Q6 ,  AP4_01 ,  E2F1DP2_01 ,  ACTGCCT_MIR34B ,  ACTGAAA_MIR30A3P_MIR30E3P ,  RAAGNYNNCTTY_UNKNOWN ,  TAATAAT_MIR126 ,  TGCCAAR_NF1_Q6 ,  AP2_Q3 ,  TGTTTGY_HNF3_Q6 ,  SOX5_01 ,  E2F1DP1_01 ,  AREB6_03 ,  HLF_01 ,  YGCGYRCGC_UNKNOWN ,  TTGTTT_FOXO4_01 ,  E2F1DP1RB_01 ,  AAAYRNCTG_UNKNOWN ,  STAT5A_04 ,  GATA1_05 ,  MEF2_03 ,  E2F_02 ,  TTCYNRGAA_STAT5B_01 ,  TGACAGNY_MEIS1_01 ,  ICSBP_Q6 ,  E2F4DP2_01 ,  CTTTGT_LEF1_Q2 ,  STAT5A_01 ,  TBP_01 ,  CAGCTG_AP4_Q5 ,  ZF5_B ,  SRY_02 ,  AACTTT_UNKNOWN

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-130 ,  Predicted Gene Targets for miR-133 ,  Predicted Gene Targets for miR-153 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-30-3p ,  Predicted Gene Targets for miR-326 ,  Predicted Gene Targets for miR-34 ,  Predicted Gene Targets for miR-34b ,  Predicted Gene Targets for miR-376c ,  Predicted Gene Targets for miR-493-5p

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Cytogenetic Map:

13q31.1

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