Name: | Bromazepam |
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PubChem Compound ID: | 2441 |
Description: | One of the BENZODIAZEPINES that is used in the treatment of ANXIETY DISORDERS. |
Molecular formula: | C14H10BrN3O |
Molecular weight: | 316.153 g/mol |
Synonyms: |
nchembio747-comp38; Lexomil; 7-Bromo-5-(2-pyridyl)-3H-1,4-benzodiazepin-2(1H)-one; Lexaurin; Lectopam (TN); Lekotam; D01245; KL 001; 2H-1,4-Benzodiazepin-2-one, 7-bromo-1,3-dihydro-5-(2-pyridinyl)-; DEA No. 2748.
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Name: | Bromazepam |
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Name (isomeric): | DB01558 |
Drug Type: | small molecule |
Description: | One of the BENZODIAZEPINES that is used in the treatment of ANXIETY DISORDERS. |
Synonyms: |
Bromazepamum [inn-latin]; 7-Bromo-5-(2-pyridyl)-3H-1,4-benzodiazepin-2(1H)-one; 7-Bromo-5-(2-pyridyl)-3H-1,4-benzodiaxepin-2(1H)-one
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Brand: | Calmepam, Compedium, Lectopam, Creosedin, Lexotanil, Gen-Bromazepam, Apo-Bromazepam, Ultramidol, Lexilium, Lexotan, Lekotam, Lexaurin, Nu-Bromazepam, Novo-bromazepam, Compendium, Durazanil, Somalium, Normoc, Lexomil |
Category: | Benzodiazepines, Anti-anxiety Agents, GABA Modulators, Hypnotics and Sedatives |
CAS number: | 1812-30-2 |
Indication: | For the short-term treatment of insomnia, short-term treatment of anxiety or panic attacks, if a benzodiazepine is required, and the alleviation of the symptoms of alcohol- and opiate-withdrawal. |
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Pharmacology: |
Bromazepam is a lipophilic, long-acting benzodiazepine and with sedative, hypnotic, anxiolytic and skeletal muscle relaxant properties. It does not possess any antidepressant qualities. Bromazepam shares with other benzodiazepines the risk of abuse, misuse, psychological and/or physical dependence. According to many psychiatric experts Bromazepam h...
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Mechanism of Action: | Bromazepam binds to the GABA receptor GABAA, causing a conformational change and increasing inhibitory effects of GABA. Other neurotransmitters are not influenced. |
Absorption: | Bioavailability is 84% following oral administration. |
Biotransformation: | Hepatically, via oxidative pathways (via an enzyme belonging to the Cytochrome P450 family of enzymes). |
Half Life: | 10-20 hours |
Affected organisms: | Humans and other mammals |
Drug interaction: |
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