QuickView for Bromodiphenhydramine (compound)

1808-12-4; 2-((4-Bromophenyl)phenylmethoxy)ethyl(dimethyl)ammonium chloride; Ethanamine, 2-((4-bromophenyl)phenylmethoxy)-N,N-dimethyl-, hydrochoride; Bromazine hydrochloride; EINECS 217-310-9; Ambodryl; Ethanamine, 2-((4-bromophenyl)phenylmethoxy)-N,N-dimethyl-, hydrochloride; Ethanamine, 2-((4-bromophenyl)phenylmethoxy)-N,N-dimethyl-, hydrochloride (9CI); ETHYLAMINE, 2-((p-BROMO-alpha-PHENYLBENZYL)OXY)-N,N-DIMETHYL-, HYDROCHLORIDE; 2-((p-Bromo-alpha-phenylbenzyl)oxy)-N,N-dimethylethylamine hydrochloride.
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1808-12-4; 2-((4-Bromophenyl)phenylmethoxy)ethyl(dimethyl)ammonium chloride; Ethanamine, 2-((4-bromophenyl)phenylmethoxy)-N,N-dimethyl-, hydrochoride; Bromazine hydrochloride; EINECS 217-310-9; Ambodryl; Ethanamine, 2-((4-bromophenyl)phenylmethoxy)-N,N-dimethyl-, hydrochloride; Ethanamine, 2-((4-bromophenyl)phenylmethoxy)-N,N-dimethyl-, hydrochloride (9CI); ETHYLAMINE, 2-((p-BROMO-alpha-PHENYLBENZYL)OXY)-N,N-DIMETHYL-, HYDROCHLORIDE; 2-((p-Bromo-alpha-phenylbenzyl)oxy)-N,N-dimethylethylamine hydrochloride; Bromdiphenhydramine hydrochloride; Bromdiphenylhydramine hydrochloride; Bromodiphenhydramine hydrochloride; NSC 36113; 118-23-0; 2-(4-Bromobenzohydryloxy)-ethyl-dimethylamine hydrochloride; 4-Bromo-alpha-phenylbenzyl 2-dimethylaminoethyl ether; beta-(p-Bromobenzhydryloxy)ethyldimethylamine hydrochloride
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Bromazine hydrochloride; Amodryl; Bromdiphenhydramine; Bromazine; Bromazin; Bromanautine; Bromdiphenhydramine hydrochloride; Bromodiphenhydramine hydrochloride; Ambodryl Hydrochloride; Bromdiphenylhydramine Hydrochloride

Bromodiphenhydramine is an antihistamine of the ethanolamine class. Ethanolamine antihistamines have significant antimuscarinic activity and produce marked sedation in most patients. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. It also is used comm...
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Bromodiphenhydramine is an antihistamine of the ethanolamine class. Ethanolamine antihistamines have significant antimuscarinic activity and produce marked sedation in most patients. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease. Rather than preventing the release of histamine, as do cromolyn and nedocromil, Bromodiphenhydramine competes with free histamine for binding at HA-receptor sites. Bromodiphenhydramine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Ethanolamine derivatives have greater anticholinergic activity than do other antihistamines, which probably accounts for the antidyskinetic action of Bromodiphenhydramine. This anticholinergic action appears to be due to a central antimuscarinic effect, which also may be responsible for its antiemetic effects, although the exact mechanism is unknown.
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