QuickView for C1QB (gene)

Gene Symbol:

C1QB Homo sapiens

Full name:

complement C1q B chain

Synonyms:

complement C1q subcomponent subunit B, complement C1q chain B, complement component 1, q subcomponent, B chain, complement component 1, q subcomponent, beta polypeptide, complement component C1q, B chain, complement subcomponent C1q chain B

Genomic Location:

Chr 1: 22852269-22860616

Description:

This gene encodes the B-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q glob...

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This gene encodes the B-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. C1q deficiency is associated with lupus erythematosus and glomerulonephritis.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

SMAD3_Q6

Cytogenetic Map:

1p36.12

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