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QuickView for C5a (gene)


Gene Symbol:
Hc Mus musculus Mus musculus
Full name:
hemolytic complement
Synonyms:
C5, C5a, He, complement C5
Genomic Location:
Chr 2: 34838851-34916916
Description:
This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin an...
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_010406
XM_017315669
Protein Names
A2AS36
P06684



GO Molecular Function

endopeptidase inhibitor activity | enzyme inhibitor activity | molecular function regulator | peptidase inhibitor activity | enzyme regulator activity

GO Biological Process

positive regulation of immune response | regulation of leukocyte chemotaxis | adaptive immune response | endopeptidase inhibitor activity | negative regulation of immune system process | regulation of localization | complement activation | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | defense response | positive regulation of protein secretion | negative regulation of proteolysis | positive regulation of chemokine secretion | cellular process | regulation of cell motility | regulation of chemotaxis | regulation of proteolysis | negative regulation of cell migration | negative regulation of macrophage migration | negative regulation of cellular metabolic process | negative regulation of cell motility | regulation of angiogenesis | regulation of immune response | regulation of cellular process | regulation of metabolic process | negative regulation of chemotaxis | regulation of peptide secretion | regulation of vasculature development | response to stimulus | enzyme inhibitor activity | positive regulation of immune system process | response to stress | positive regulation of vascular endothelial growth factor production | negative regulation of leukocyte chemotaxis | positive regulation of cytokine secretion | regulation of protein transport | negative regulation of metabolic process | regulation of peptide transport | embryo development | molecular function regulator | positive regulation of peptide secretion | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | nitrogen compound metabolic process | multicellular organism development | negative regulation of catalytic activity | regulation of peptidase activity | leukocyte mediated immunity | regulation of catalytic activity | negative regulation of peptidase activity | complement activation, alternative pathway | positive regulation of secretion | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cellular component movement | regulation of cellular protein metabolic process | positive regulation of chemokine production | protein activation cascade | regulation of leukocyte migration | chordate embryonic development | regulation of cellular metabolic process | humoral immune response | inflammatory response | regulation of protein metabolic process | positive regulation of establishment of protein localization | regulation of locomotion | embryo development ending in birth or egg hatching | positive regulation of transport | regulation of cytokine secretion | activation of immune response | protein metabolic process | regulation of establishment of protein localization | anatomical structure development | complement activation, classical pathway | metabolic process | regulation of secretion | immune response | organic substance metabolic process | negative regulation of cellular protein metabolic process | negative regulation of cellular component movement | regulation of protein secretion | negative regulation of macrophage chemotaxis | positive regulation of cytokine production | positive regulation of protein transport | negative regulation of protein metabolic process | humoral immune response mediated by circulating immunoglobulin | negative regulation of molecular function | peptidase inhibitor activity | enzyme regulator activity | regulation of cytokine production | regulation of endopeptidase activity | negative regulation of leukocyte migration | regulation of developmental process | B cell mediated immunity | developmental process | regulation of chemokine production | regulation of transport | innate immune response | cytolysis | regulation of vascular endothelial growth factor production | negative regulation of hydrolase activity | regulation of macrophage chemotaxis | in utero embryonic development | immunoglobulin mediated immune response | immune system process | regulation of protein localization | negative regulation of locomotion | positive regulation of angiogenesis | negative regulation of endopeptidase activity | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

integral component of membrane | cell | plasma membrane protein complex | intrinsic component of membrane | protein-containing complex | plasma membrane | integral component of plasma membrane | extracellular region | extracellular space | cell periphery | pore complex | membrane attack complex | membrane | intrinsic component of plasma membrane