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QuickView for C6;jsessionid=64EE3FB6B9C8693E79AC5B369EF2B336 (gene)


Gene Symbol:
C6 Homo sapiens Homo sapiens
Full name:
complement C6
Synonyms:
complement component C6, complement component 6
Genomic Location:
Chr 5: 41178093-41249369
Description:
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 5
5p13.1





GO Molecular Function

protein binding

GO Biological Process

positive regulation of immune response | adaptive immune response | complement activation | regulation of immune system process | positive regulation of developmental process | defense response | cellular process | positive regulation of immune effector process | regulation of proteolysis | positive regulation of nitrogen compound metabolic process | regulation of angiogenesis | regulation of immune response | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | positive regulation of protein processing | regulation of vasculature development | response to stimulus | positive regulation of immune system process | positive regulation of protein metabolic process | response to stress | positive regulation of activation of membrane attack complex | regulation of humoral immune response | positive regulation of proteolysis | regulation of protein processing | embryo development | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | nitrogen compound metabolic process | multicellular organism development | leukocyte mediated immunity | regulation of acute inflammatory response | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | positive regulation of humoral immune response | regulation of cellular protein metabolic process | protein activation cascade | regulation of complement activation | chordate embryonic development | regulation of cellular metabolic process | humoral immune response | regulation of protein metabolic process | embryo development ending in birth or egg hatching | activation of immune response | protein metabolic process | anatomical structure development | complement activation, classical pathway | metabolic process | positive regulation of complement activation | immune response | organic substance metabolic process | humoral immune response mediated by circulating immunoglobulin | positive regulation of protein maturation | regulation of developmental process | B cell mediated immunity | developmental process | innate immune response | cytolysis | in utero embryonic development | positive regulation of metabolic process | immunoglobulin mediated immune response | immune system process | regulation of inflammatory response | positive regulation of angiogenesis | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

integral component of membrane | cell | plasma membrane protein complex | intrinsic component of membrane | protein-containing complex | plasma membrane | vesicle | extracellular exosome | integral component of plasma membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cell periphery | pore complex | membrane attack complex | membrane | intrinsic component of plasma membrane