QuickView for C8G (gene)
- Gene Symbol:
- C8G
Homo sapiens - Full name:
- complement C8 gamma chain
- Synonyms:
- C8C, complement component C8 gamma chain, complement component 8, gamma polypeptide
- Genomic Location:
- Chr 9: 138959534-138961240
- Description:
-
The protein encoded by this gene belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell memb...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Canis lupus familiaris , Bos taurus , Gallus gallus
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
9q34.3
GO Molecular Function
isoprenoid binding | retinoid binding | protein-containing complex binding | complement binding | lipid binding | vitamin binding | alcohol binding | protein binding | retinol binding | small molecule binding
GO Biological Process
positive regulation of immune response | adaptive immune response | complement activation | regulation of immune system process | defense response | cellular process | regulation of proteolysis | regulation of immune response | regulation of metabolic process | response to stimulus | positive regulation of immune system process | response to stress | regulation of humoral immune response | regulation of protein processing | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | nitrogen compound metabolic process | leukocyte mediated immunity | regulation of acute inflammatory response | regulation of gene expression | complement activation, alternative pathway | regulation of nitrogen compound metabolic process | protein activation cascade | regulation of complement activation | humoral immune response | regulation of protein metabolic process | activation of immune response | protein metabolic process | complement activation, classical pathway | metabolic process | immune response | organic substance metabolic process | humoral immune response mediated by circulating immunoglobulin | B cell mediated immunity | innate immune response | cytolysis | immunoglobulin mediated immune response | immune system process | regulation of inflammatory response | macromolecule metabolic process
GO Cellular Component
integral component of membrane | cell | plasma membrane protein complex | intrinsic component of membrane | protein-containing complex | plasma membrane | vesicle | extracellular exosome | integral component of plasma membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cell periphery | pore complex | membrane attack complex | blood microparticle | membrane | intrinsic component of plasma membrane
