QuickView for CACH6 (gene)

Gene Symbol:

CACNA1E Homo sapiens

Full name:

calcium voltage-gated channel subunit alpha1 E

Synonyms:

BII, CACH6, CACNL1A6, Cav2.3, gm139, voltage-dependent R-type calcium channel subunit alpha-1E, brain calcium channel II, calcium channel, L type, alpha-1 polypeptide, calcium channel, R type, alpha-1 polypeptide, voltage-dependent calcium channel alpha 1E subunit, voltage-gated calcium channel alpha subunit Cav2.3

Genomic Location:

Chr 1: 179719339-180037339

Description:

Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene e...

View Full Description

Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  STAT4_01 ,  AAGCCAT_MIR135A_MIR135B ,  CCCAGAG_MIR326 ,  NGFIC_01 ,  CTTTGCA_MIR527 ,  PEA3_Q6 ,  SRY_01 ,  TEF1_Q6 ,  P53_02 ,  CAGGTG_E12_Q6 ,  ATACCTC_MIR202 ,  CACCAGC_MIR138 ,  CAGCTTT_MIR320 ,  TGCTGAY_UNKNOWN ,  MEIS1AHOXA9_01 ,  TTGTTT_FOXO4_01 ,  CHOP_01 ,  WTTGKCTG_UNKNOWN ,  TGATTTRY_GFI1_01 ,  CTTTGT_LEF1_Q2 ,  EGR1_01 ,  SRY_02 ,  AACTTT_UNKNOWN ,  YNGTTNNNATT_UNKNOWN ,  NFKB_Q6 ,  ETF_Q6 ,  GGGTGGRR_PAX4_03 ,  OLF1_01

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-135 ,  Predicted Gene Targets for miR-138 ,  Predicted Gene Targets for miR-143 ,  Predicted Gene Targets for miR-183 ,  Predicted Gene Targets for miR-30-3p ,  Predicted Gene Targets for miR-320 ,  Predicted Gene Targets for miR-326 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-182

Cytogenetic Map:

1q25.3

search → result