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QuickView for CACNA1B (gene)

Gene Symbol:
CACNA1B Homo sapiens Homo sapiens
Full name:
calcium voltage-gated channel subunit alpha1 B
BIII, CACNL1A5, CACNN, Cav2.2, DYT23, voltage-dependent N-type calcium channel subunit alpha-1B, Cav2.2 voltage-gated Ca2+ channel, brain calcium channel III, calcium channel alpha12.2 subunit, calcium channel, L type, alpha-1 polypeptide, calcium channel, voltage-dependent, L type, alpha 1B subunit, calcium channel, voltage-dependent, N type, alpha 1B subunit, voltage-gated calcium channel alpha subunit Cav2.2, voltage-gated calcium channel subunit alpha Cav2.2
Genomic Location:
Chr 9: 139892062-140136449
The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin...
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 9

Transcripts Names

GO Molecular Function

voltage-gated ion channel activity | cation binding | passive transmembrane transporter activity | ribonucleotide binding | transmembrane transporter activity | nucleotide binding | ion gated channel activity | carbohydrate derivative binding | voltage-gated calcium channel activity | ATP binding | anion binding | adenyl nucleotide binding | cation transmembrane transporter activity | purine nucleotide binding | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | metal ion transmembrane transporter activity | voltage-gated cation channel activity | cation channel activity | calcium ion binding | inorganic cation transmembrane transporter activity | purine ribonucleotide binding | voltage-gated channel activity | adenyl ribonucleotide binding | channel activity | drug binding | calcium channel activity | metal ion binding | ion channel activity | heterocyclic compound binding | protein C-terminus binding | substrate-specific channel activity | small molecule binding

GO Biological Process

neurotransmitter secretion | regulation of localization | establishment of localization | voltage-gated ion channel activity | calcium ion import | cellular process | secretion | localization | passive transmembrane transporter activity | metal ion transport | chemical synaptic transmission | establishment of localization in cell | transmembrane transporter activity | response to stimulus | ion gated channel activity | response to pain | response to stress | regulation of blood circulation | cellular localization | divalent metal ion transport | secretion by cell | blood circulation | cell-cell signaling | regulation of membrane potential | voltage-gated calcium channel activity | regulation of neurotransmitter levels | calcium ion transmembrane transport | ion transmembrane transport | regulation of blood pressure | synaptic signaling | cation transmembrane transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | locomotory behavior | regulation of heart contraction | cell communication | cation transmembrane transport | multicellular organismal response to stress | metal ion transmembrane transporter activity | voltage-gated cation channel activity | calcium ion transport | behavior | membrane depolarization | inorganic cation transmembrane transport | regulation of ion transmembrane transport | cation channel activity | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | voltage-gated channel activity | cation transport | channel activity | regulation of ion transport | calcium channel activity | regulation of calcium ion transport | regulation of transport | neurotransmitter transport | signal release | ion channel activity | ion transport | substrate-specific channel activity | multicellular organismal process

GO Cellular Component

integral component of membrane | dendrite | synapse | neuron projection | somatodendritic compartment | voltage-gated calcium channel complex | cell body | cell | neuronal cell body | plasma membrane protein complex | intrinsic component of membrane | dendritic tree | presynapse | protein-containing complex | cell projection | plasma membrane | calcium channel complex | cell periphery | transmembrane transporter complex | cation channel complex | ion channel complex | membrane