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QuickView for CACNB1 (gene)


Gene Symbol:
CACNB1 Homo sapiens Homo sapiens
Full name:
calcium voltage-gated channel auxiliary subunit beta 1
Synonyms:
CAB1, CACNLB1, CCHLB1, voltage-dependent L-type calcium channel subunit beta-1, calcium channel voltage-dependent subunit beta 1, calcium channel, L type, beta 1 polypeptide, calcium channel, voltage-dependent, beta 1 subunit, dihydropyridine-sensitive L-type, calcium channel beta-1 subunit
Genomic Location:
Chr 17: 34583235-34607427
Description:
The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Danio rerio Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 17
17q12





GO Molecular Function

high voltage-gated calcium channel activity | voltage-gated ion channel activity | passive transmembrane transporter activity | transmembrane transporter activity | ion gated channel activity | voltage-gated calcium channel activity | cation transmembrane transporter activity | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | metal ion transmembrane transporter activity | voltage-gated cation channel activity | cation channel activity | inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | calcium channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

regulation of localization | high voltage-gated calcium channel activity | establishment of localization | voltage-gated ion channel activity | cellular process | localization | passive transmembrane transporter activity | metal ion transport | chemical synaptic transmission | regulation of calcium ion transmembrane transport via high voltage-gated calcium channel | transmembrane transporter activity | cellular response to organonitrogen compound | cellular component organization | response to stimulus | ion gated channel activity | response to peptide | divalent metal ion transport | cell-cell signaling | voltage-gated calcium channel activity | response to nitrogen compound | calcium ion transmembrane transport | ion transmembrane transport | cellular response to peptide | synaptic signaling | cation transmembrane transporter activity | neuromuscular junction development | calcium ion transmembrane transporter activity | synapse organization | ion transmembrane transporter activity | regulation of calcium ion transmembrane transport | regulation of voltage-gated calcium channel activity | cell communication | cellular response to amyloid-beta | cation transmembrane transport | response to organic substance | metal ion transmembrane transporter activity | voltage-gated cation channel activity | calcium ion transport | inorganic cation transmembrane transport | regulation of ion transmembrane transport | cation channel activity | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | response to amyloid-beta | regulation of transmembrane transporter activity | regulation of ion transmembrane transporter activity | voltage-gated channel activity | cation transport | channel activity | regulation of ion transport | calcium channel activity | regulation of calcium ion transport | regulation of transport | regulation of cation channel activity | response to organonitrogen compound | ion channel activity | regulation of calcium ion transmembrane transporter activity | ion transport | cellular response to organic substance | substrate-specific channel activity

GO Cellular Component

integral component of membrane | sarcolemma | voltage-gated calcium channel complex | cell | plasma membrane protein complex | intrinsic component of membrane | protein-containing complex | plasma membrane | calcium channel complex | cell periphery | transmembrane transporter complex | cation channel complex | ion channel complex | membrane