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QuickView for CALM2 (gene)


Gene Symbol:
CALM2 Homo sapiens Homo sapiens
Full name:
calmodulin 2
Synonyms:
CAMII, LQT15, PHKD, PHKD2, caM, calmodulin-2, LP7057 protein, calmodulin 2 (phosphorylase kinase, delta), phosphorylase kinase delta, phosphorylase kinase subunit delta, prepro-calmodulin 2
Genomic Location:
Chr 2: 47240809-47257154
Description:
This gene is a member of the calmodulin gene family. There are three distinct calmodulin genes dispersed throughout the genome that encode the identical protein, but differ at the nucleotide level. Calmodulin is a calcium binding protein that plays a role in signaling pathways, cell cycle progression and proliferation. Several infants with severe f...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 2
2p21


Protein Names
Q96HY3



GO Molecular Function

protein kinase activator activity | protein serine/threonine kinase activator activity | kinase binding | enzyme activator activity | protein kinase regulator activity | protein phosphatase activator activity | channel regulator activity | cation binding | adenylate cyclase binding | kinase regulator activity | protein kinase binding | enzyme binding | disordered domain specific binding | ion channel inhibitor activity | phosphatase activator activity | molecular function regulator | ion channel binding | protein domain specific binding | protein N-terminus binding | channel inhibitor activity | cytoskeletal protein binding | adenylate cyclase activator activity | ion binding | protein binding | calcium channel regulator activity | N-terminal myristoylation domain binding | kinase activator activity | protein phosphatase regulator activity | calcium ion binding | titin binding | calcium channel inhibitor activity | enzyme regulator activity | metal ion binding | phosphatase regulator activity

GO Biological Process

positive regulation of release of sequestered calcium ion into cytosol | negative regulation of phosphorylation | brain development | regulation of muscle system process | regulation of cell cycle process | protein kinase activator activity | regulation of dephosphorylation | protein serine/threonine kinase activator activity | detection of stimulus | positive regulation of ion transmembrane transporter activity | regulation of cellular localization | intracellular signal transduction | enzyme activator activity | regulation of localization | protein kinase regulator activity | positive regulation of peptidyl-threonine phosphorylation | positive regulation of phosphoprotein phosphatase activity | negative regulation of cellular process | regulation of phosphatase activity | response to metal ion | positive regulation of cyclic-nucleotide phosphodiesterase activity | nervous system development | negative regulation of protein phosphorylation | cellular chemical homeostasis | regulation of cell communication by electrical coupling involved in cardiac conduction | positive regulation of phosphate metabolic process | positive regulation of cation channel activity | protein phosphatase activator activity | interaction with symbiont | positive regulation of dephosphorylation | cellular process | channel regulator activity | cellular homeostasis | regulation of calcium-mediated signaling | negative regulation of signaling | kinase regulator activity | positive regulation of protein kinase activity | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | response to inorganic substance | negative regulation of cellular metabolic process | regulation of binding | interspecies interaction between organisms | regulation of cellular process | regulation of metabolic process | positive regulation of ryanodine-sensitive calcium-release channel activity | regulation of cytosolic calcium ion concentration | positive regulation of cellular protein metabolic process | negative regulation of calcium-mediated signaling | calcium ion homeostasis | regulation of cell division | head development | response to stimulus | negative regulation of peptidyl-threonine phosphorylation | ion channel inhibitor activity | positive regulation of protein metabolic process | phosphatase activator activity | positive regulation of cation transmembrane transport | regulation of cardiac muscle contraction by calcium ion signaling | regulation of blood circulation | positive regulation of phosphatase activity | regulation of heart rate | negative regulation of transporter activity | midbrain development | negative regulation of transport | regulation of DNA binding | G-protein coupled receptor signaling pathway | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | negative regulation of calcium ion transmembrane transport | negative regulation of transmembrane transport | positive regulation of protein dephosphorylation | activation of protein kinase activity | molecular function regulator | metal ion homeostasis | regulation of calcium ion transport into cytosol | system development | regulation of signal transduction | detection of chemical stimulus | negative regulation of phosphate metabolic process | positive regulation of calcium ion transmembrane transport | channel inhibitor activity | multicellular organism development | detection of calcium ion | adenylate cyclase activator activity | regulation of muscle contraction | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | cell cycle | regulation of protein autophosphorylation | modification of morphology or physiology of other organism | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | positive regulation of ion transmembrane transport | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | negative regulation of release of sequestered calcium ion into cytosol | positive regulation by host of symbiont cAMP-mediated signal transduction | positive regulation of intracellular signal transduction | substantia nigra development | positive regulation of hydrolase activity | second-messenger-mediated signaling | positive regulation of calcium-mediated signaling | regulation of release of sequestered calcium ion into cytosol | negative regulation of ion transmembrane transport | negative regulation of calcium ion transmembrane transporter activity | regulation of cellular protein metabolic process | G2/M transition of mitotic cell cycle | negative regulation of ion transport | regulation of calcium ion transmembrane transport | regulation of heart contraction | mitotic cell cycle phase transition | cation homeostasis | regulation of striated muscle contraction | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of cytokinesis | negative regulation of cation channel activity | positive regulation of transporter activity | positive regulation of sequestering of calcium ion | negative regulation of calcium ion transport | regulation of cardiac muscle contraction | regulation of protein metabolic process | positive regulation of signal transduction | regulation of cAMP-mediated signaling | cellular calcium ion homeostasis | cell cycle G2/M phase transition | homeostatic process | regulation of protein phosphorylation | positive regulation of transport | negative regulation of calcium ion transport into cytosol | positive regulation of molecular function | calcium-mediated signaling | regulation of ryanodine-sensitive calcium-release channel activity | calcium channel regulator activity | positive regulation of protein modification process | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | regulation of protein dephosphorylation | regulation of kinase activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | anatomical structure development | kinase activator activity | mitotic cell cycle | chemical homeostasis | negative regulation of ion transmembrane transporter activity | regulation of sequestering of calcium ion | regulation of cell communication by electrical coupling | animal organ development | positive regulation of ion transport | negative regulation of cellular protein metabolic process | protein phosphatase regulator activity | positive regulation of cAMP-mediated signaling | positive regulation of kinase activity | ion homeostasis | regulation of phosphate metabolic process | regulation of ion transmembrane transport | positive regulation of binding | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | positive regulation of DNA binding | positive regulation of calcium ion transmembrane transporter activity | calcium channel inhibitor activity | regulation of transmembrane transporter activity | regulation of ion transmembrane transporter activity | positive regulation of phosphorylation | enzyme regulator activity | positive regulation of calcium ion transport into cytosol | regulation of ion transport | regulation of phosphoprotein phosphatase activity | developmental process | negative regulation of ryanodine-sensitive calcium-release channel activity | regulation of cardiac conduction | regulation of calcium ion transport | positive regulation of protein autophosphorylation | regulation of transport | regulation of cation channel activity | cell cycle phase transition | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion | cellular metal ion homeostasis | response to calcium ion | central nervous system development | positive regulation of metabolic process | regulation of calcium ion transmembrane transporter activity | divalent inorganic cation homeostasis | positive regulation of calcium ion transport | phosphatase regulator activity | positive regulation of signaling | neural nucleus development | signal transduction | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

supramolecular fiber | integral component of membrane | intracellular membrane-bounded organelle | catalytic complex | potassium channel complex | sarcomere | microtubule organizing center | cell | plasma membrane protein complex | intrinsic component of membrane | myofibril | microtubule | cytoplasm | spindle | intracellular organelle | contractile fiber | centrosome | protein-containing complex | plasma membrane | vesicle | microtubule cytoskeleton | voltage-gated potassium channel complex | spindle pole | integral component of plasma membrane | spindle microtubule | calcium channel complex | membrane-bounded organelle | nucleus | organelle | cell periphery | transmembrane transporter complex | cation channel complex | ion channel complex | cytoskeleton | intracellular | myelin sheath | membrane | supramolecular complex | intrinsic component of plasma membrane