QuickView for CALM3 (gene)
- Gene Symbol:
- CALM3
Homo sapiens - Full name:
- calmodulin 3
- Synonyms:
- CaM, CaMIII, HEL-S-72, PHKD, PHKD3, calmodulin-3, epididymis secretory protein Li 72, phosphorylase kinase subunit delta, prepro-calmodulin 3
- Genomic Location:
- Chr 19: 51796352-51805879
- Description:
-
This gene encodes a member of a family of proteins that binds calcium and functions as a enzymatic co-factor. Activity of this protein is important in the regulation of the cell cycle and cytokinesis. Multiple alternatively spliced transcript variants have been observed at this gene.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-122a , Predicted Gene Targets for miR-196 , Predicted Gene Targets for miR-22 , Predicted Gene Targets for miR-25 , Predicted Gene Targets for miR-27 , Predicted Gene Targets for miR-320 , Predicted Gene Targets for miR-330 , Predicted Gene Targets for miR-361 , Predicted Gene Targets for miR-29
- Cytogenetic Map:
-
19q13.32
| Transcripts Names |
|---|
| NM_005184 |
| NM_001329921 |
| NM_001329924 |
| NM_001329926 |
| NM_001329925 |
| NM_001329922 |
| NM_001329923 |
GO Molecular Function
protein kinase activator activity | phosphatidylinositol 3-kinase binding | protein serine/threonine kinase activator activity | kinase binding | enzyme activator activity | protein kinase regulator activity | protein phosphatase activator activity | cation binding | adenylate cyclase binding | kinase regulator activity | protein kinase binding | G-protein coupled glutamate receptor binding | enzyme binding | disordered domain specific binding | signaling receptor binding | phosphatase activator activity | molecular function regulator | ion channel binding | protein domain specific binding | protein N-terminus binding | cytoskeletal protein binding | adenylate cyclase activator activity | calcium-dependent protein binding | ion binding | protein binding | N-terminal myristoylation domain binding | kinase activator activity | nitric-oxide synthase binding | G-protein coupled receptor binding | nitric-oxide synthase regulator activity | protein phosphatase regulator activity | calcium ion binding | titin binding | enzyme regulator activity | type 3 metabotropic glutamate receptor binding | metal ion binding | glutamate receptor binding | phosphatase regulator activity
GO Biological Process
positive regulation of release of sequestered calcium ion into cytosol | negative regulation of phosphorylation | brain development | regulation of muscle system process | regulation of cell cycle process | protein kinase activator activity | regulation of dephosphorylation | protein serine/threonine kinase activator activity | detection of stimulus | positive regulation of ion transmembrane transporter activity | regulation of cellular localization | intracellular signal transduction | enzyme activator activity | protein localization to mitochondrion | regulation of localization | protein kinase regulator activity | positive regulation of peptidyl-threonine phosphorylation | establishment of localization | response to hormone | positive regulation of phosphoprotein phosphatase activity | negative regulation of cellular process | regulation of phosphatase activity | response to metal ion | positive regulation of cyclic-nucleotide phosphodiesterase activity | nervous system development | response to drug | negative regulation of protein phosphorylation | cellular chemical homeostasis | regulation of cell communication by electrical coupling involved in cardiac conduction | positive regulation of phosphate metabolic process | positive regulation of cation channel activity | membrane organization | protein phosphatase activator activity | interaction with symbiont | positive regulation of dephosphorylation | cellular process | localization | cellular homeostasis | regulation of calcium-mediated signaling | negative regulation of signaling | kinase regulator activity | establishment of protein localization to mitochondrion | positive regulation of nitric-oxide synthase activity | positive regulation of protein kinase activity | macromolecule localization | positive regulation of oxidoreductase activity | response to corticosterone | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | response to inorganic substance | establishment of localization in cell | negative regulation of cellular metabolic process | regulation of binding | interspecies interaction between organisms | regulation of cellular process | regulation of metabolic process | positive regulation of ryanodine-sensitive calcium-release channel activity | regulation of cytosolic calcium ion concentration | positive regulation of cellular protein metabolic process | cellular component organization | negative regulation of calcium-mediated signaling | calcium ion homeostasis | regulation of cell division | head development | response to stimulus | negative regulation of peptidyl-threonine phosphorylation | positive regulation of protein metabolic process | phosphatase activator activity | positive regulation of cation transmembrane transport | establishment of protein localization to mitochondrial membrane | regulation of cardiac muscle contraction by calcium ion signaling | regulation of blood circulation | positive regulation of phosphatase activity | regulation of high voltage-gated calcium channel activity | regulation of heart rate | negative regulation of transporter activity | cellular localization | response to alcohol | midbrain development | negative regulation of transport | regulation of DNA binding | G-protein coupled receptor signaling pathway | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | modulation of chemical synaptic transmission | mitochondrion organization | negative regulation of calcium ion transmembrane transport | negative regulation of transmembrane transport | positive regulation of protein dephosphorylation | activation of protein kinase activity | regulation of intracellular transport | molecular function regulator | metal ion homeostasis | regulation of neurotransmitter levels | positive regulation of monooxygenase activity | response to nitrogen compound | regulation of calcium ion transport into cytosol | system development | regulation of signal transduction | detection of chemical stimulus | negative regulation of phosphate metabolic process | positive regulation of calcium ion transmembrane transport | multicellular organism development | detection of calcium ion | regulation of synaptic vesicle exocytosis | adenylate cyclase activator activity | regulation of muscle contraction | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of nitric-oxide synthase activity | protein localization to membrane | response to ketone | response to lipid | cell cycle | regulation of protein autophosphorylation | modification of morphology or physiology of other organism | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | positive regulation of ion transmembrane transport | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | negative regulation of release of sequestered calcium ion into cytosol | positive regulation by host of symbiont cAMP-mediated signal transduction | positive regulation of intracellular signal transduction | response to corticosteroid | substantia nigra development | protein localization to organelle | positive regulation of hydrolase activity | second-messenger-mediated signaling | positive regulation of calcium-mediated signaling | regulation of release of sequestered calcium ion into cytosol | negative regulation of ion transmembrane transport | negative regulation of calcium ion transmembrane transporter activity | regulation of cellular protein metabolic process | G2/M transition of mitotic cell cycle | negative regulation of ion transport | regulation of calcium ion transmembrane transport | regulation of synaptic vesicle endocytosis | regulation of synaptic vesicle transport | response to toxic substance | regulation of voltage-gated calcium channel activity | response to xenobiotic stimulus | regulation of heart contraction | mitotic cell cycle phase transition | cation homeostasis | regulation of striated muscle contraction | mitochondrial membrane organization | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of cytokinesis | negative regulation of cation channel activity | positive regulation of transporter activity | positive regulation of sequestering of calcium ion | negative regulation of calcium ion transport | regulation of cardiac muscle contraction | regulation of protein metabolic process | positive regulation of signal transduction | regulation of cAMP-mediated signaling | cellular calcium ion homeostasis | cell cycle G2/M phase transition | homeostatic process | regulation of protein phosphorylation | positive regulation of transport | negative regulation of calcium ion transport into cytosol | positive regulation of molecular function | calcium-mediated signaling | regulation of ryanodine-sensitive calcium-release channel activity | establishment of protein localization to membrane | activation of adenylate cyclase activity | positive regulation of protein modification process | response to organic substance | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | regulation of protein dephosphorylation | regulation of kinase activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | regulation of exocytosis | establishment of protein localization to organelle | anatomical structure development | kinase activator activity | response to amine | mitotic cell cycle | response to mineralocorticoid | cellular protein localization | regulation of vesicle-mediated transport | nitric-oxide synthase regulator activity | chemical homeostasis | regulation of secretion | negative regulation of ion transmembrane transporter activity | regulation of sequestering of calcium ion | regulation of cell communication by electrical coupling | animal organ development | positive regulation of ion transport | negative regulation of cellular protein metabolic process | protein phosphatase regulator activity | positive regulation of cAMP-mediated signaling | positive regulation of kinase activity | ion homeostasis | regulation of phosphate metabolic process | regulation of ion transmembrane transport | positive regulation of binding | establishment of protein localization | regulation of regulated secretory pathway | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of oxidoreductase activity | response to organic cyclic compound | positive regulation of DNA binding | regulation of endocytosis | positive regulation of calcium ion transmembrane transporter activity | regulation of transmembrane transporter activity | protein localization | regulation of ion transmembrane transporter activity | positive regulation of phosphorylation | enzyme regulator activity | cellular macromolecule localization | positive regulation of calcium ion transport into cytosol | regulation of synaptic vesicle recycling | regulation of ion transport | regulation of phosphoprotein phosphatase activity | developmental process | organelle organization | negative regulation of ryanodine-sensitive calcium-release channel activity | regulation of cardiac conduction | regulation of calcium ion transport | positive regulation of protein autophosphorylation | regulation of transport | regulation of cation channel activity | response to organonitrogen compound | cell cycle phase transition | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion | cellular metal ion homeostasis | regulation of calcium ion-dependent exocytosis | response to calcium ion | central nervous system development | positive regulation of metabolic process | regulation of calcium ion transmembrane transporter activity | response to amphetamine | response to steroid hormone | divalent inorganic cation homeostasis | regulation of cellular component organization | positive regulation of calcium ion transport | phosphatase regulator activity | positive regulation of signaling | neural nucleus development | signal transduction | regulation of signaling | response to glucocorticoid | regulation of neurotransmitter secretion | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
supramolecular fiber | exocytic vesicle | integral component of membrane | intracellular membrane-bounded organelle | synapse | catalytic complex | neuron projection | potassium channel complex | organelle membrane | sarcomere | microtubule organizing center | cytoplasmic vesicle | cell | plasma membrane protein complex | distal axon | intrinsic component of membrane | transport vesicle membrane | myofibril | microtubule | cytoplasm | spindle | intracellular organelle | contractile fiber | presynapse | centrosome | protein-containing complex | cell projection | secretory vesicle | endomembrane system | plasma membrane | exocytic vesicle membrane | vesicle | transport vesicle | microtubule cytoskeleton | voltage-gated potassium channel complex | mitochondrion | site of polarized growth | spindle pole | integral component of plasma membrane | spindle microtubule | synaptic vesicle | calcium channel complex | membrane-bounded organelle | nucleus | organelle | vesicle membrane | mitochondrial envelope | cell periphery | axon | transmembrane transporter complex | growth cone | cation channel complex | ion channel complex | synaptic vesicle membrane | mitochondrial membrane | intracellular vesicle | cytoskeleton | intracellular | myelin sheath | membrane | supramolecular complex | cytoplasmic vesicle membrane | intrinsic component of plasma membrane
