QuickView for CALML5;jsessionid=AD65C3EB86F0F0468439D279AB974EB3 (gene)

Gene Symbol:

CALML5 Homo sapiens

Full name:

calmodulin like 5

Synonyms:

CLSP, calmodulin-like protein 5, calmodulin-like skin protein

Genomic Location:

Chr 10: 5530660-5531510

Description:

This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is rest...

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This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GGGAGGRR_MAZ_Q6 ,  GGGTGGRR_PAX4_03

Cytogenetic Map:

10p15.1

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